Evidence map›Paper›PMID 41279649›Full record

ArticlebioRxiv : the preprint server for biology2025

Rapid generation of ventral A9-like dopaminergic neurons from patterned iPSCs.

Kriti Chaplot, Lin Zhang, Julia Wessman, Miguel Rivera, Zhihui Wang, Fei Wang, Xin Duan, Pamela M England, Iain C Clark, Erik M Ullian

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kriti ChaplotDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0002-8939-4696
Lin ZhangDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94158, USA.
Julia WessmanDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94158, USA.
Miguel RiveraDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94158, USA.
Zhihui WangDepartment of Bioengineering, University of California Berkeley, Berkeley, CA 94720, USA.
Fei WangDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94158, USA.
Xin DuanDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94158, USA.
Pamela M EnglandDepartment of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA.
Iain C ClarkDepartment of Bioengineering, University of California Berkeley, Berkeley, CA 94720, USA.
Erik M UllianDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94158, USA.

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ULLIAN, ERIK M · 1985 to 2024
$16.8M
Mechanisms Underlying Type II Cadherin Guided Assembly of Retinal CircuitsR01EY030138 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Xin Duan · 2020 to 2026
$3.2M
Mechanistic analysis and allellic genome editing of iPSC-derived dominant LCA modelR01EY032197 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ULLIAN, ERIK M · 2021 to 2025
$2.5M
Vision Bioinformatics and ComputationP30EY037668 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Erik M Ullian · 2025 to 2026
$2.0M
Defining Roles of Perivascular Retinal Neurons by Integrating Visual Stimuli and Vascular TonesK99EY036489 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, FEI · 2024 to 2025
$234k
NEI NIH HHS K99 EY036489NEI NIH HHS P30 EY002162NEI NIH HHS P30 EY037668NEI NIH HHS R01 EY030138NEI NIH HHS R01 EY032197
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3D assembled organoidsA9-substantia nigraastrocytesdopaminergic differentiationmicrogliamidbrain specificitymultielectrode arrayParkinson’s diseaseselective vulnerabilitysingle-cell transcriptomic analysis

Identifiers

PMID41279649
PMCPMC12636497

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.