Evidence map›Paper›PMID 41279618›Full record

ArticlebioRxiv : the preprint server for biology2025

The effect of spontaneous mutations on

Rohan Sohoni, Gillian G Schatz, Nathaniel P Sharp

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Rohan SohoniDepartment of Genetics, University of Wisconsin-Madison, 425-G Henry Mall, Madison, WI, USA.
Gillian G SchatzDepartment of Genetics, University of Wisconsin-Madison, 425-G Henry Mall, Madison, WI, USA.
Nathaniel P SharpDepartment of Genetics, University of Wisconsin-Madison, 425-G Henry Mall, Madison, WI, USA.ORCID 0000-0001-6016-083X

Funding

The evolutionary and genomic drivers of mutation spectraR35GM154954 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Nathaniel Sharp · 2024 to 2026
$1.1M
NIGMS NIH HHS R35 GM154954
6 · The paper itself

Abstract

Genomic regions containing tandem duplications may be subject to particularly high rates of copy number mutations due to recombinational repair of DNA damage. Consequently, changes in copy number may be among the most accessible beneficial mutations during evolution in a new environment. In the budding yeast

Indexed as

gene duplicationmitotic recombinationmutational variance

Identifiers

PMID41279618
PMCPMC12637435

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.