Evidence map›Paper›PMID 41279606›Full record

ArticlebioRxiv : the preprint server for biology2025

Sensitivity to ATR-CHK1 pathway inhibition in AML/MDS is enhanced by

Samuli Eldfors, Sumit Rai, Vineet Sharma, Tareq Hossan, Claudia Cabrera Pastrana, Amy Bertino, Angelique Gilbert, Kimmo Porkka, Matthew Walter, Timothy A Graubert

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Samuli EldforsMass General Brigham Cancer Institute, Boston, MA, USA.ORCID 0000-0001-5056-4750
Sumit RaiMass General Brigham Cancer Institute, Boston, MA, USA.
Vineet SharmaMass General Brigham Cancer Institute, Boston, MA, USA.ORCID 0000-0002-5481-6051
Tareq HossanDivision of Oncology, Department of Medicine, Washington University School of Medicine.ORCID 0000-0003-4625-2900
Claudia Cabrera PastranaDivision of Oncology, Department of Medicine, Washington University School of Medicine.ORCID 0000-0002-9748-2020
Amy BertinoMass General Brigham Cancer Institute, Boston, MA, USA.
Angelique GilbertMass General Brigham Cancer Institute, Boston, MA, USA.
Kimmo PorkkaDepartment of Medicine, Clinic, Faculty of Medicine, University of Helsinki.ORCID 0000-0003-4112-5902
Matthew WalterDivision of Oncology, Department of Medicine, Washington University School of Medicine.ORCID 0000-0002-7753-1091
Timothy A GraubertMass General Brigham Cancer Institute, Boston, MA, USA.ORCID 0000-0002-7710-1171

Funding

Targeting the Bone Marrow Microenvironment In Acute Lymphocytic LeukemiaP50CA171963 · NCI · WASHINGTON UNIVERSITY · PI Daniel C Link · 2013 to 2026
$31.6M
NCI NIH HHS P50 CA171963
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41279606
PMCPMC12632562

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.