Evidence map›Paper›PMID 41279556›Full record

ArticlebioRxiv : the preprint server for biology2025

Tubulin autoregulation factors SCAPER and TTC5 recruit γ-tubulin to non-centrosomal MTOCs for neuronal microtubule nucleation and axon regeneration.

Yi Xie, Alessandro Comincini, Chengye Feng, Carrie Ann Davison, Marc Hammarlund, Francesca Bartolini, Shaul Yogev

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi XieDepartment of Neuroscience, Yale University School of Medicine, 100 College St, New Haven, CT 06510.ORCID 0000-0003-1936-0121
Alessandro CominciniDepartment of Pathology & Cell Biology, Columbia University Medical Center, 630 W. 168th Street, New York, NY 10032.
Chengye FengDepartment of Neuroscience, Yale University School of Medicine, 100 College St, New Haven, CT 06510.
Carrie Ann DavisonDepartment of Neuroscience, Yale University School of Medicine, 100 College St, New Haven, CT 06510.ORCID 0000-0002-2358-207X
Marc HammarlundDepartment of Neuroscience, Yale University School of Medicine, 100 College St, New Haven, CT 06510.ORCID 0000-0002-3068-068X
Francesca BartoliniDepartment of Pathology & Cell Biology, Columbia University Medical Center, 630 W. 168th Street, New York, NY 10032.
Shaul YogevDepartment of Neuroscience, Yale University School of Medicine, 100 College St, New Haven, CT 06510.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
New Mechanisms in Axon RegenerationR01NS094219 · NINDS · YALE UNIVERSITY · PI HAMMARLUND, MARC · 2015 to 2025
$4.0M
Pathogenic Roles for Microtubule Stabilization Pathways in Alzheimers diseaseR01AG050658 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Francesca Bartolini · 2016 to 2026
$3.5M
Patterning acentrosomal microtubule arraysR35GM133573 · NIGMS · YALE UNIVERSITY · PI Shaul Yogev · 2019 to 2026
$3.2M
NIA NIH HHS R01 AG050658NIGMS NIH HHS R35 GM133573NIH HHS P40 OD010440NINDS NIH HHS R01 NS094219
6 · The paper itself

Abstract

Neuronal function and survival depend on highly stereotyped non-centrosomal microtubule (MT) arrays. How these arrays form remains poorly understood. Here we identified a role for SCAPER and TTC5, two factors previously implicated in

Identifiers

PMID41279556
PMCPMC12632806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.