Evidence map›Paper›PMID 41279512›Full record

ArticlebioRxiv : the preprint server for biology2025

ADAPT-M: A workflow for rapid, quantitative

Carla P Perez, Nicole V DelRosso, Cameron L Noland, Udit Parekh, Christian A Choe, Raphael R Eguchi, Qi Wen, Polly M Fordyce, Po-Ssu Huang

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Carla P PerezBiophysics Program, Stanford University, Stanford, CA, USA.ORCID 0000-0002-9154-2360
Nicole V DelRossoBiophysics Program, Stanford University, Stanford, CA, USA.ORCID 0000-0003-4339-3353
Cameron L NolandDiscovery Chemistry, Merck & Co., Inc., South San Francisco, CA, USA.ORCID 0000-0001-6364-3167
Udit ParekhDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID 0000-0002-6395-1781
Christian A ChoeDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID 0000-0001-8871-9682
Raphael R EguchiDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID 0000-0002-2704-8464
Qi WenDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Polly M FordyceBiophysics Program, Stanford University, Stanford, CA, USA.ORCID 0000-0002-9505-0638
Po-Ssu HuangBiophysics Program, Stanford University, Stanford, CA, USA.ORCID 0000-0002-7948-2895

Funding

Using microfluidics to realize patient-specific anti-cancer immunotherapiesDP1CA290563 · NCI · STANFORD UNIVERSITY · PI Polly Morrell Fordyce · 2023 to 2026
$5.4M
Generative neural networks for structure-based antibody designR01GM147893 · NIGMS · STANFORD UNIVERSITY · PI Possu Huang · 2022 to 2026
$1.9M
Stanford Chem-H Chemistry/Biology Interface Predoctoral Training ProgramT32GM120007 · NIGMS · STANFORD UNIVERSITY · PI BERTOZZI, CAROLYN · 2016 to 2020
$1.2M
NCI NIH HHS DP1 CA290563NIGMS NIH HHS R01 GM147893NIGMS NIH HHS T32 GM120007
6 · The paper itself

Abstract

Protein-protein interactions underpin most cellular interactions, and engineered binders present powerful tools for probing biology and developing novel therapeutics. One bottleneck in binder generation is the scalable, quantitative characterization of these interactions. We present ADAPT-M (

Identifiers

PMID41279512
PMCPMC12633381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.