Evidence map›Paper›PMID 41279491›Full record

ArticlebioRxiv : the preprint server for biology2025

Mutating different α-tubulin acetylation sites has distinct effects on axon terminal morphogenesis in

Helen Than, Chloe J Welch, Ethan Schauer, Sophia Truijillo, Jill Wildonger

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Helen ThanPediatrics, University of California, San Diego, La Jolla, CA 92093.
Chloe J WelchBiological Sciences Graduate Program, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0002-8330-4901
Ethan SchauerPediatrics, University of California, San Diego, La Jolla, CA 92093.ORCID 0009-0009-2833-7119
Sophia TruijilloSchool of Biological Sciences, Cell & Developmental Biology, University of California, San Diego, La Jolla, CA 92093.
Jill WildongerPediatrics, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0002-6462-5830

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Pathways in Biological Sciences Training ProgramT32GM133351 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Matthew Daugherty, Randolph Y. Hampton · 2020 to 2026
$9.9M
Mechanistic analysis of microtubule dynamics and stability in neuronsR01NS116373 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WILDONGER, JILL C · 2021 to 2025
$1.7M
NIGMS NIH HHS T32 GM133351NIH HHS P40 OD018537NINDS NIH HHS R01 NS116373
6 · The paper itself

Abstract

Microtubules are created from uniform α- and β-tubulin building blocks but typically carry out a variety of specialized functions within a cell. The post-translational modification of tubulin is one means by which microtubule function can be tuned to match different cellular activities. While multiple sites of acetylation have been identified in tubulin, particularly α-tubulin, the effect of acetylation at different sites on microtubule function remains poorly characterized. Here, we took a genetic approach in

Identifiers

PMID41279491
PMCPMC12636568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.