ArticlebioRxiv : the preprint server for biology2025
On the Mechanism of Ezrin Activation.
Dovydas Vasiliauskas, Jeriann Beiter, Sahithya Sridharan Iyer, Andrew T Lombardo, Michelle C Mendoza, Gregory A Voth
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors.
Dovydas VasiliauskasDepartment of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637.
Jeriann BeiterDepartment of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637.
Sahithya Sridharan IyerDepartment of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637.
Andrew T LombardoDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, 14203.ORCID 0000-0002-1814-5748 Michelle C MendozaDepartment of Oncological Sciences, University of Utah, Salt Lake City, UT 84112.
Gregory A VothDepartment of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637.
Funding
Beagle-3: A Shared GPU Cluster for Biomolecular SciencesS10OD028655 · OD · UNIVERSITY OF CHICAGO · PI ROUX, BENOIT · 2020 to 2020
$2.0MMultiscale Simulation of Key Biomolecular Processes in the CellR35GM158238 · NIGMS · UNIVERSITY OF CHICAGO · PI VOTH, GREGORY A. · 2025 to 2025
$2.0MKinase Control of Synergistic Cell Migration MechanicsR01GM141372 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Michelle Christine Mendoza · 2022 to 2026
$1.6MThe Cytoskeletal Drivers of Cell PolarityR35GM156870 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Andrew Thomas Lombardo · 2025 to 2026
$757kNIGMS NIH HHS R01 GM141372NIGMS NIH HHS R35 GM156870NIGMS NIH HHS R35 GM158238NIH HHS S10 OD028655
6 · The paper itselfAbstract
Ezrin is a peripheral membrane protein that contributes to the organization and stability of cellular membrane structures by reversibly linking the plasma membrane to actin filaments. The formation of this membrane-actin linkage has been experimentally shown to require ezrin N-terminal (FERM) domain binding to PI(4,5)P
Identifiers
PMID41279471
PMCPMC12637478
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