Evidence map›Paper›PMID 41279469›Full record

ArticlebioRxiv : the preprint server for biology2025

Genome-wide DNA bridging by H-NS reshapes the stationary phase nucleoid and transcriptional landscape.

Lindsey E Way, Xiaofeng Dai, Emma E Wiesler, Lauren A McCarthy, Zhongqing Ren, Gail G Hardy, David E H Fuller, Labeeb Hossain, Anne S Meyer, Elio A Abbondanzieri and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lindsey E WayDepartment of Biology, Indiana University, 1001 E 3 Street, Bloomington, IN 47405, USA.
Xiaofeng DaiDepartment of Chemistry, University of Michigan, 930 N. University Ave., Ann Arbor, MI 48109, USA.
Emma E WieslerDepartment of Biology, Indiana University, 1001 E 3 Street, Bloomington, IN 47405, USA.
Lauren A McCarthyDepartment of Chemistry, University of Michigan, 930 N. University Ave., Ann Arbor, MI 48109, USA.
Zhongqing RenDepartment of Biology, Indiana University, 1001 E 3 Street, Bloomington, IN 47405, USA.
Gail G HardyDepartment of Biology, Indiana University, 1001 E 3 Street, Bloomington, IN 47405, USA.
David E H FullerDepartment of Chemistry, University of Michigan, 930 N. University Ave., Ann Arbor, MI 48109, USA.
Labeeb HossainDepartment of Biology, Indiana University, 1001 E 3 Street, Bloomington, IN 47405, USA.
Anne S MeyerDepartment of Biology, University of Rochester, Rochester, NY, 14627, USA.
Elio A AbbondanzieriDepartment of Biology, University of Rochester, Rochester, NY, 14627, USA.
Julie S BiteenDepartment of Chemistry, University of Michigan, 930 N. University Ave., Ann Arbor, MI 48109, USA.ORCID 0000-0003-2038-6484
Xindan WangDepartment of Biology, Indiana University, 1001 E 3 Street, Bloomington, IN 47405, USA.ORCID 0000-0001-6458-180X

Funding

Michigan IRACDA: Training Future Professors of Engineering and PhysiologyK12GM111725 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, SUSAN V, SEPT, DAVID · 2016 to 2025
$7.9M
Physicochemical properties driving membraneless organelle assembly in bacteriaR01GM143182 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BITEEN, JULIE, MEYER, ANNE SARA · 2021 to 2024
$2.4M
Determining the molecular basis of gene silencing by MucR and defining its role in Brucella virulenceR01AI172822 · NIAID · EAST CAROLINA UNIVERSITY · PI ROY M ROOP · 2023 to 2026
$2.3M
How bacterial SMC complexes organize chromosomes (Equipment Supplement)R01GM141242 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI WANG, XINDAN · 2021 to 2025
$1.8M
NIAID NIH HHS R01 AI172822NIGMS NIH HHS K12 GM111725NIGMS NIH HHS R01 GM141242NIGMS NIH HHS R01 GM143182
6 · The paper itself

Abstract

Bacterial nucleoid-associated proteins (NAPs) structure the chromosome and regulate gene expression, but how these two functions are related is unclear. H-NS is a well-studied NAP that acts as a global gene silencer capable of bridging and looping DNA

Indexed as

ChIP-seqHi-CH-NSPhotoactivated Localization MicroscopyRNA-seqSingle-Molecule TrackingSingle-Particle Tracking

Identifiers

PMID41279469
PMCPMC12632814

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.