Evidence map›Paper›PMID 41279399›Full record

ArticlebioRxiv : the preprint server for biology2025

Mucinolysome in gut microbiomes of farm animals and humans.

Jerry Elorm Akresi, Thi Van Thanh Do, Zhisong Cui, N R Siva Shanmugam, Sarah Moraïs, Itzhak Mizrahi, Edward A Bayer, Jennifer Auchtung, Yanbin Yin

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jerry Elorm AkresiNebraska Food for Health Center, Department of Food Science and Technology, University of Nebraska - Lincoln, Lincoln, NE 68588, USA.
Thi Van Thanh DoNebraska Food for Health Center, Department of Food Science and Technology, University of Nebraska - Lincoln, Lincoln, NE 68588, USA.
Zhisong CuiNebraska Food for Health Center, Department of Food Science and Technology, University of Nebraska - Lincoln, Lincoln, NE 68588, USA.
N R Siva ShanmugamNebraska Food for Health Center, Department of Food Science and Technology, University of Nebraska - Lincoln, Lincoln, NE 68588, USA.
Sarah MoraïsDepartment of Life Sciences, Ben-Gurion University of the Negev, 8410501, Be'er Sheva, Israel.
Itzhak MizrahiDepartment of Life Sciences, Ben-Gurion University of the Negev, 8410501, Be'er Sheva, Israel.
Edward A BayerDepartment of Life Sciences, Ben-Gurion University of the Negev, 8410501, Be'er Sheva, Israel.
Jennifer AuchtungNebraska Food for Health Center, Department of Food Science and Technology, University of Nebraska - Lincoln, Lincoln, NE 68588, USA.
Yanbin YinNebraska Food for Health Center, Department of Food Science and Technology, University of Nebraska - Lincoln, Lincoln, NE 68588, USA.

Funding

Exploration of cloud computing for CAZyme researchR01GM140370 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI YIN, YANBIN · 2021 to 2024
$1.5M
Glycan Utilization Profiling in Human Gut Microbiomes of Common Funds DataR03OD039979 · OD · UNIVERSITY OF NEBRASKA LINCOLN · PI YIN, YANBIN · 2025 to 2025
$294k
NIGMS NIH HHS R01 GM140370NIH HHS R03 OD039979
6 · The paper itself

Abstract

Mucins are glycoproteins that create a protective barrier protecting host tissues from microbial pathogens and are instrumental for host health. Here, we provide evidence that mucin glycan degradation in the gut can be mediated by mucinolysomes, defined as extracellular multi-enzyme complexes specializing in mucin glycan degradation. We computationally predicted the presence of mucinolysomes across 63 metagenome-assembled genomes (MAGs) and two isolated genomes of anaerobic

Indexed as

AnaeromassilibacillusCAZymecellulosomegut microbiomeLimousiamucinmucinolysome

Identifiers

PMID41279399
PMCPMC12632915

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.