Evidence map›Paper›PMID 41279397›Full record

ArticlebioRxiv : the preprint server for biology2025

Inducible Calling Cards: Developing Mouse Reagents for Experimentally Controlled Transposon Insertion

Simona Sarafinovska, Arthi Venkatesan, Titilope Akinwe, Alexander Chamessian, Xuhua Chen, Maria Payne, Meaghan C Creed, Robi D Mitra, Joseph D Dougherty

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simona SarafinovskaDepartment of Genetics, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0002-1456-7556
Arthi VenkatesanDepartment of Genetics, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0009-0003-4354-5799
Titilope AkinweDepartment of Genetics, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0002-9406-7497
Alexander ChamessianWashington University Pain Center, Department of Anesthesiology, St. Louis, MO, USA.ORCID 0000-0002-7775-2062
Xuhua ChenDepartment of Genetics, Washington University School of Medicine, Saint Louis, MO, USA.
Maria PayneWashington University Pain Center, Department of Anesthesiology, St. Louis, MO, USA.ORCID 0000-0001-5584-046X
Meaghan C CreedWashington University Pain Center, Department of Anesthesiology, St. Louis, MO, USA.ORCID 0000-0002-9658-2601
Robi D MitraDepartment of Genetics, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0002-2680-4264
Joseph D DoughertyDepartment of Genetics, Washington University School of Medicine, Saint Louis, MO, USA.ORCID 0000-0002-6385-3997

Funding

WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JEFFREY D MILBRANDT · 2020 to 2026
$15.5M
INSTITUTIONAL TRAINING GRANT IN GENOMIC SCIENCET32HG000045 · NHGRI · WASHINGTON UNIVERSITY · PI MICHAEL R BRENT, Barak A Cohen · 1997 to 2026
$8.4M
Genomic and functional characterization of ASD and ID-associated MYT1L mutationR01MH124808 · NIMH · WASHINGTON UNIVERSITY · PI KROLL, KRISTEN L · 2021 to 2025
$3.7M
Molecular recording to predict cell fate decisions and animal behaviorRF1MH126723 · NIMH · WASHINGTON UNIVERSITY · PI DOUGHERTY, JOSEPH D, MITRA, ROBI D · 2021 to 2021
$3.7M
PARALLEL ANALYSIS OF TRANSCRIPTION AND PROTEIN-DNAINTERACTIONS IN SINGLE CNS CELLSRF1MH117070 · NIMH · WASHINGTON UNIVERSITY · PI DOUGHERTY, JOSEPH D, MITRA, ROBI D · 2018 to 2020
$3.2M
NHGRI NIH HHS T32 HG000045NICHD NIH HHS P50 HD103525NIMH NIH HHS R01 MH124808NIMH NIH HHS RF1 MH117070NIMH NIH HHS RF1 MH126723
6 · The paper itself

Abstract

The piggyBac transposase enables robust forward genetic screens in mice. Further, fusions of piggyBac with specific transcription factors (TFs) enables recovery of recoverable transposons (Calling Cards) for recording location of DNA binding events

Identifiers

PMID41279397
PMCPMC12637670

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.