Evidence map›Paper›PMID 41279255›Full record

ArticlebioRxiv : the preprint server for biology2025

Detoxifying and depolymerizing microorganisms reveal intertwined guild collaborations in the gut microbiome of a generalist macro-algivorous fish.

Alvaro M Plominsky, Aaron Oliver, Carlos Henriquez-Castillo, Sheila Podell, Jeremiah J Minich, Simona Augyte, Jennica Lowell-Hawkins, Neil A Sims, Eric E Allen

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Alvaro M PlominskyCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.
Aaron OliverCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-0410-8284
Carlos Henriquez-CastilloDepartment of Biology, Baylor University, Waco, TX, USA.
Sheila PodellCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-7073-5190
Jeremiah J MinichOcean-Era, Inc., Kailua-Kona, Hawaii, USA.
Simona AugyteOcean-Era, Inc., Kailua-Kona, Hawaii, USA.
Jennica Lowell-HawkinsOcean-Era, Inc., Kailua-Kona, Hawaii, USA.
Neil A SimsOcean-Era, Inc., Kailua-Kona, Hawaii, USA.
Eric E AllenCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-1229-8794

Funding

Natural Sources and Microbial Transformation of Marine Halogenated PollutantsR01ES030316 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALLEN, ERIC ELLSWORTH, MOORE, BRADLEY S · 2018 to 2022
$669k
Acquisition of Covaris E220 and Sciclone G3 systems for high throughput sequencinS10OD010786 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COMAI, LUCA · 2012 to 2012
$311k
NIEHS NIH HHS R01 ES030316NIH HHS S10 OD010786
6 · The paper itself

Abstract

The biotransformation of macroalgal biomass represents a major catabolic challenge due to its structurally diverse polysaccharides and inhibitory polyphenols. Unlike terrestrial lignocellulosic substrates, macroalgae polysaccharides contain multiple monomer types, branching patterns, and sulfation states. Additionally, macroalgae polyphenols have been shown to inhibit both microbial growth and their catalytic enzymes. While herbivorous fishes have evolved specialized gut microbiota to process these substrates, the enzymatic pathways remain poorly characterized, with few experimentally validated polysaccharide utilization loci or biochemically defined marine sulfatases, and limited understanding of polyphenol degradation. Here, we developed

Indexed as

fish gut microbiomemacroalgal digestionpolyphenol utilizationpolysaccharide utilizationsulfatases

Identifiers

PMID41279255
PMCPMC12637443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.