Evidence map›Paper›PMID 41279227›Full record

ArticlebioRxiv : the preprint server for biology2025

Multilayer control of KaiR1D-autoreceptor function by the auxiliary protein Neto.

Wen-Chieh Hsieh, Tae Hee Han, Rosario Vicidomini, Peter Nguyen, Zheng Li, Mihaela Serpe

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen-Chieh HsiehSection on Cellular Communication, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, 20892, USA.
Tae Hee HanSection on Cellular Communication, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, 20892, USA.ORCID 0000-0001-6223-9437
Rosario VicidominiSection on Cellular Communication, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, 20892, USA.
Peter NguyenSection on Cellular Communication, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, 20892, USA.
Zheng LiSection on Synapse Development Plasticity, National Institute of Mental Health, NIH, Bethesda, MD, 20892, USA.ORCID 0000-0002-2978-2531
Mihaela SerpeSection on Cellular Communication, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, 20892, USA.ORCID 0000-0002-9205-8589

Funding

Non-apoptotic function of casapses in synapsesZIAMH002881 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI LI, ZHENG · 2009 to 2025
$18.9M
Mechanisms of synapse developmentZIAHD008914 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SERPE, MIHAELA · 2011 to 2025
$16.4M
Modulation of TGF-beta signalingZIAHD008869 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SERPE, MIHAELA · 2009 to 2025
$8.0M
Intramural NIH HHS ZIA HD008869Intramural NIH HHS ZIA HD008914Intramural NIH HHS ZIA MH002881
6 · The paper itself

Abstract

Kainate-type glutamate receptors and their dedicated auxiliary protein Neto function at both pre- and postsynaptic sites to regulate the activity of synaptic networks. However, attributing specific synaptic functions to Neto and/or kainate receptors is challenging. Here we focus on

Identifiers

PMID41279227
PMCPMC12632606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.