Evidence map›Paper›PMID 41279205›Full record

ArticlebioRxiv : the preprint server for biology2025

Maternal Influenza A Virus Infection Induces Antiviral and Immune Dysregulation in the Placenta and Fetus Without Vertical Transmission.

Orlando Cervantes, Sidney Sun, Hazel Huang, Briana M Del Rosario, Hong Zhao, Amanda Li, Andrew E Vo, Gygeria Manuel, Roslyn Van Abel, Jeff Munson and 24 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors.

Orlando CervantesORCID 0000-0003-3187-9567
Hazel Huang
Briana M Del RosarioORCID 0009-0007-8449-3234
Hong Zhao
Gygeria Manuel
Roslyn Van Abel
Edmunda Li
Hanning Li
Alexandra Christodoulou
Elizabeth Miller
Shannon Ruff
Brenna A Menz
Solomon N Wangari
Audrey Germond
Audrey Baldessari
Chris English
W McIntyre Durning
Megan N FredericksORCID 0009-0002-8865-9688
Austyn Orvis
Lakshmi RajagopalORCID 0000-0003-3373-2323
Kristina M Adams WaldorfORCID 0000-0002-6939-7224

Funding

Influenza pathogenesis in pregnancyR01AI164588 · NIAID · UNIVERSITY OF WASHINGTON · PI ADAMS WALDORF, KRISTINA M. · 2021 to 2025
$4.2M
NIAID NIH HHS R01 AI164588
6 · The paper itself

Abstract

Influenza A virus (IAV) infection during pregnancy is associated with stillbirth and preterm birth, but the degree to which IAV alters placental and fetal immunity is poorly understood. The objective of our study was to determine the immunologic impact of maternal IAV infection on the placenta and fetus in a pigtail macaque (Macaca nemestrina) model. Pregnant pigtail macaques were inoculated with 10

Identifiers

PMID41279205
PMCPMC12632329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.