Evidence map›Paper›PMID 41279185›Full record

ArticlebioRxiv : the preprint server for biology2025

BayesCurveFit: Enhancing Curve Fitting for Early-Stage Compound Screening Using Bayesian Inference.

Niu Du, Yang Chen, Yu Qian

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Niu DuJ. Craig Venter Institute, La Jolla, CA, USA.
Yang ChenDepartment of Statistics, University of Michigan, Ann Arbor, MI, USA.
Yu QianJ. Craig Venter Institute, La Jolla, CA, USA.ORCID 0000-0001-7894-5926

Funding

The Development and Evaluation of Pan-Coronavirus VaccinesP01AI168347 · NIAID · WASHINGTON UNIVERSITY · PI Michael S Diamond · 2022 to 2026
$15.9M
Integrated analysis of HBV-specific CD4 T cell and B cell responses to define their role in chronic hepatitis B and HBV functional cure.R01AI184931 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI GEORG Michael LAUER, Mansun Law · 2024 to 2026
$3.6M
Influenza Modeling of Correlates of Protection for Optimal Immune Dynamics and Evolution.U01AI187057 · NIAID · EMORY UNIVERSITY · PI Rafael A. Medina Silva, Gene Brian Tan · 2025 to 2026
$2.3M
NIAID NIH HHS P01 AI168347NIAID NIH HHS R01 AI184931NIAID NIH HHS U01 AI187057
6 · The paper itself

Abstract

Accurate curve fitting is central to quantifying dose-response relationships in drug discovery. However, commonly used regression-based methods are ill-suited for early prescreening assays, where measurements are sparse and experimental noise can dominate. Bayesian approaches have been developed previously, but they are rarely optimized for such data-limited, noise-prone conditions. We present

Identifiers

PMID41279185
PMCPMC12637442

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.