Evidence map›Paper›PMID 41279182›Full record

ArticlebioRxiv : the preprint server for biology2025

Sulfatase modifying factors control the timing of zebrafish convergence and extension morphogenesis.

Ailen Soledad Cervino, Amrita Basu, Ryan J Weiss, Gursimran Kaur Bajwa, Rubén Marín Juez, Sandra Grimm, Cristian Coarfa, Margot Kossmann Williams

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Ailen Soledad CervinoCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA.
Amrita BasuComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
Ryan J WeissComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
Gursimran Kaur BajwaCentre de Recherche Azrieli, Centre Hospitalier Universitaire Sainte-Justine, Montréal, QC, Canada.
Rubén Marín JuezCentre de Recherche Azrieli, Centre Hospitalier Universitaire Sainte-Justine, Montréal, QC, Canada.
Sandra GrimmCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA.
Cristian CoarfaCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA.
Margot Kossmann WilliamsCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA.

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
Project 5: Pyolytic conversion of PAHs in contaminated sediments into char to eliminate toxicity and enhance soil fertilityP42ES027725 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Nagireddy Putluri · 2020 to 2026
$17.8M
Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
National Glycoscience Resource- CCRC Service and Training - NGlycoR@CCRCR24GM137782 · NIGMS · UNIVERSITY OF GEORGIA · PI Parastoo Azadi · 2020 to 2026
$5.2M
Molecular drivers of tissue-specific morphogenetic programsR01HD104784 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Margot L.K. Williams · 2022 to 2026
$2.2M
Developmental Reprogramming of Prostate Carcinogenesis by BPARC2ES018789 · NIEHS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HO, SHUK-MEI, MANCINI, MICHAEL A. · 2009 to 2010
$1.9M
Investigating the molecular mechanisms of glycosaminoglycan assemblyR35GM150736 · NIGMS · UNIVERSITY OF GEORGIA · PI Ryan Joseph Weiss · 2023 to 2026
$1.5M
Defining Direct and Indirect Roles of Nodal Signaling in Convergence & ExtensionR00HD091386 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI WILLIAMS, MARGOT L.K. · 2020 to 2022
$680k
High Memory High-Performance Computer Cluster for Biomedical ResearchS10OD032185 · OD · BAYLOR COLLEGE OF MEDICINE · PI HILSENBECK, SUSAN G. · 2022 to 2022
$596k
NCI NIH HHS P30 CA125123NICHD NIH HHS R00 HD091386NICHD NIH HHS R01 HD104784NIEHS NIH HHS P30 ES030285NIEHS NIH HHS P42 ES027725NIEHS NIH HHS RC2 ES018789NIGMS NIH HHS R24 GM137782NIGMS NIH HHS R35 GM150736NIH HHS S10 OD032185
6 · The paper itself

Abstract

To shape the emerging body plan, morphogenetic cell movements must be coordinated not only in space, but also in time. Convergence and Extension (C&E) movements that elongate the anteroposterior axis initiate with precise timing during vertebrate gastrulation, but the mechanisms controlling their onset remain unknown. We examined this question using zebrafish embryonic explants that faithfully recapitulate C&E cell movements and their precise timing in culture, in isolation from other gastrulation movements. We determined that new transcription is required at gastrulation onset for C&E in explants and identified

Indexed as

convergence and extensiongastrulationHSPGsSulf1Sumf1Sumf2zebrafish

Identifiers

PMID41279182
PMCPMC12632512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.