Evidence map›Paper›PMID 41279177›Full record

ArticlebioRxiv : the preprint server for biology2025

A genetically-defined population of amygdalofugal neurons promotes suckling and early postnatal growth.

Jeffrey D Moore, Lukas C Bachmann, Lauren E McElvain, Samuel L Pfaff, Catherine Dulac

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeffrey D MooreHoward Hughes Medical Institute, Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, MA, USA.
Lukas C BachmannGene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Lauren E McElvainDepartment of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
Samuel L PfaffGene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Catherine DulacHoward Hughes Medical Institute, Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, MA, USA.

Funding

Spinal Circuits for the Control of Dextrous MovementU19NS112959 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI AZIM, EIMAN · 2019 to 2023
$14.3M
Microcircuits underlying murine parental behaviorR01HD082131 · NICHD · HARVARD UNIVERSITY · PI DULAC, CATHERINE · 2015 to 2024
$3.5M
Characterization of spinal circuits underlying motor synergy functionR01NS123160 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI PFAFF, SAMUEL L. · 2021 to 2025
$3.0M
Descending engagement of brainstem neuronal circuits that govern orofacial motor behaviorsR00HD096512 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MOORE, JEFFREY DANIEL · 2023 to 2025
$744k
Descending engagement of brainstem neuronal circuits that govern orofacial motor behaviorsK99HD096512 · NICHD · HARVARD UNIVERSITY · PI MOORE, JEFFREY DANIEL · 2018 to 2019
$179k
NICHD NIH HHS K99 HD096512NICHD NIH HHS R00 HD096512NICHD NIH HHS R01 HD082131NINDS NIH HHS R01 NS123160NINDS NIH HHS U19 NS112959
6 · The paper itself

Abstract

Suckling by newborns is an instinctive behavior defining the mammalian class. Yet, due to experimental difficulty in assessing neural function in the very young, little is known about the neural control of this fundamental behavior. Here we develop molecular-genetic approaches to interrogate neuronal connectivity and function in newborn mice and used these tools to identify a population of pro-dynorphin (PDYN) and somatostatin (SST) expressing neurons in the central amygdala that are activated during suckling. CeA

Identifiers

PMID41279177
PMCPMC12632880

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.