Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Jiemin ShenDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0000-0002-3977-0681
Teja Nikhil PeddadaDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0000-0002-5132-2064
Konstantin E KomolovDepartment of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.ORCID 0000-0001-6799-4626
Francesco De PascaliDepartment of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.ORCID 0000-0002-5880-3725
Alexander M GarcesDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0003-0160-2487
Haoqing WangDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0000-0003-0277-3018
Michael T LerchDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0002-8173-4879
Jeffrey L BenovicDepartment of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Jun XuDepartment of Medical Neuroscience, SUSTech Homeostatic Medicine Institute, School of Medicine, Institute for Biology Electron Microscopy, Southern University of Science and Technology, Shenzhen, Guangdong, 518067, China.ORCID 0000-0002-1600-583X
Brian K KobilkaDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0000-0001-5958-3990
Funding
Project 4 - OGR1- and TSPO- dependent mechanisms mediated by benzodiazepines affecting ASM contractionP01HL114471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LIGGETT, STEPHEN B · 2013 to 2023
$23.9M
The Stanford-SLAC CryoEM CenterR24GM154186 · NIGMS · STANFORD UNIVERSITY · PI Wah Chiu, BRITT HEDMAN · 2024 to 2026
$19.3M
Structure and dynamics of G protein coupled receptor-G protein complexesR01GM083118 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KOBILKA, BRIAN K, SKINIOTIS, GEORGIOS · 2008 to 2023
$8.3M
Novel Biased Beta2-AR Ligands as Asthma TherapeuticsR01AI161296 · NIAID · DUKE UNIVERSITY · PI CHU, HONG W, DICKEY, BURTON F · 2021 to 2025
$3.2M
G protein coupled receptor structure, dynamics, and signaling.R35NS137408 · NINDS · STANFORD UNIVERSITY · PI Brian K Kobilka · 2024 to 2026
$1.9M
Regulation of β2-adrenergic receptor signaling by post-translational modificationsR01GM135581 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI LERCH, MICHAEL TAYLOR · 2019 to 2023
$1.7M
Upgrades to a Bruker Q-band E580 Pulse EPR SpectrometerS10OD025260 · OD · MEDICAL COLLEGE OF WISCONSIN · PI KLUG, CANDICE S · 2019 to 2019
Family A G-protein coupled receptors (GPCRs) are typically described as monomers, yet growing evidence suggests they can form dimers with distinct signaling properties
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
A biased allosteric modulator functions as a molecular glue to induce β · full record | OpenQuestion