Evidence map›Paper›PMID 41279045›Full record

ArticlebioRxiv : the preprint server for biology2025

Sequestration of clock proteins into repressive nuclear condensates orchestrates circadian gene repression.

Qianqian Chen, Ye Yuan, Dunham Clark, Swathi Yadlapalli

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qianqian ChenDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Ye YuanCellular and Molecular Biology Graduate Program, University of Michigan, Ann Arbor, MI 48109.
Dunham ClarkDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Swathi YadlapalliDepartment of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.

Funding

Spatiotemporal mechanisms controlling circadian rhythmsR35GM133737 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Swathi Yadlapalli · 2019 to 2026
$3.4M
Deciphering the Role of mRNA Nuclear Localization in Circadian RhythmsR01NS140761 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Swathi Yadlapalli · 2025 to 2026
$746k
NIGMS NIH HHS R35 GM133737NINDS NIH HHS R01 NS140761
6 · The paper itself

Abstract

Circadian clocks orchestrate ~24-hour cycles in gene expression, behavior, and physiology across most organisms

Identifiers

PMID41279045
PMCPMC12637644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.