Evidence map›Paper›PMID 41279037›Full record

ArticlebioRxiv : the preprint server for biology2025

Dynamic

Zhipeng Tao, Ritesh P Thakare, Melyssa Cheung, Jianan Zhang, Xin Chen, Xiaodi Hu, Brian G Pierce, Xu Wu, Junhao Mao

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Zhipeng TaoCutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Ritesh P ThakareDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
Melyssa CheungDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Jianan ZhangCutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Xin ChenDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
Xiaodi HuDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
Brian G PierceDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
Xu WuCutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Junhao MaoDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.

Funding

Targeting dynamic palmitoylation of TEAD transcription factorsR01CA238270 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI MAO, JUNHAO, WU, XU · 2019 to 2023
$2.7M
Chemical approach to study autopalmitoylation of transcription factorsR01DK107651 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI LUO, XUELIAN, WU, XU · 2016 to 2020
$1.9M
Dependence for TEAD transcription factors in intestinal development and polyposisR01DK127180 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MAO, JUNHAO · 2020 to 2024
$1.9M
Mechanism of YAP/TAZ crosstalk with Wnt signalingR01DK127207 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MAO, JUNHAO · 2021 to 2024
$1.5M
NCI NIH HHS R01 CA238270NIDDK NIH HHS R01 DK107651NIDDK NIH HHS R01 DK127180NIDDK NIH HHS R01 DK127207
6 · The paper itself

Abstract

GSDMA, the primary member of the gasdermin family found in the skin, is critical for pathogen-induced pyroptosis during infection. Recent studies revealed that another gasdermin, GSDMD, undergoes palmitoylation during pyroptosis. However, whether and how the other gasdermin members undergo lipid modification remains poorly understood. Here, we demonstrate that GSDMA is

Identifiers

PMID41279037
PMCPMC12633010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.