Evidence map›Paper›PMID 41279012›Full record

ArticlebioRxiv : the preprint server for biology2025

Mitofusin agonists enhances long-term engraftment and potency of HSC cultures

Alyssa Biondo, Gabriela Candelaria, Daniel Jin, Emily Lin, Daniel McLaughlin, Zhaolun Liang, Katherine Leong, Christopher D Hillyer, Hans-Willem Snoeck, Larry L Luchsinger

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alyssa Biondo- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.
Gabriela Candelaria- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.
Daniel Jin- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.
Emily Lin- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.
Daniel McLaughlin- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.
Zhaolun Liang- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.
Katherine Leong- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.
Christopher D Hillyer- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.
Hans-Willem Snoeck- Columbia Center for Stem Cell Regenerative Medicine, Columbia University Irving Medical Center, New York, NY 10032.
Larry L Luchsinger- Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065.

Funding

Hormetic ER Stress Regulation of Hematopoietic Stem Cell FunctionR01HL155574 · NHLBI · NEW YORK BLOOD CENTER · PI LUCHSINGER, LARRY L · 2021 to 2025
$2.5M
NHLBI NIH HHS R01 HL155574
6 · The paper itself

Abstract

Umbilical cord blood (CBU) is a valuable source of hematopoietic stem cells (HSCs) due to its superior donor compatibility and lower incidence of graft-versus-host disease. However, its limited HSC content restricts its use in adult transplantation, necessitating new targets for

Identifiers

PMID41279012
PMCPMC12636445

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.