ArticlebioRxiv : the preprint server for biology2025
CED-3 caspase promotes dismantling but not onset of non-apoptotic linker cell death in
Olya Yarychkivska, Lena M Kutscher, Dana Mamriev, Betty Ortiz Bido, Yun Lu, Wolfgang Keil, Sarit Larisch, Shai Shaham
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Dana MamrievCell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, 31905, Haifa, Israel.
Betty Ortiz BidoDevelopmental Genetics, the Rockefeller University, New York, USA.
Yun LuDevelopmental Genetics, the Rockefeller University, New York, USA.
Wolfgang KeilInstitut Curie, Université PSL, Sorbonne Université, CNRS UMR168 Laboratoire Physico Chimie Curie, Paris 75005, France.
Sarit LarischCell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, 31905, Haifa, Israel.
Funding
Glial Control of Neuron Development and Function - Administrative SupplementR35NS105094 · NINDS · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2018 to 2025
$8.9MGenetics and Cell BiologyT32GM066699 · NIGMS · ROCKEFELLER UNIVERSITY · PI STRICKLAND, SIDNEY · 2004 to 2021
$7.6MEnhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5MLinker cell death regulation in C. elegansR01HD103610 · NICHD · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2021 to 2025
$1.8MNuclear and chromatin aberrations during non-apoptotic cell death in C. elegans and mammalsK99GM151467 · NIGMS · ROCKEFELLER UNIVERSITY · PI YARYCHKIVSKA, OLGA · 2023 to 2024
$250kNICHD NIH HHS R01 HD103610NIGMS NIH HHS K99 GM151467NIGMS NIH HHS T32 GM066699NIH HHS P40 OD010440NINDS NIH HHS R35 NS105094
6 · The paper itselfAbstract
Nuclear degradation accompanies cell death. To study this process, we followed nuclear dismantling of the
Indexed as
arf-6caspaseced-3C. elegansdegradationengulfmentLCDlinker celllinker cell-type deathMEFmouse embryonic fibroblastsnon-apoptotic cell deathnuclear crenellationrab-35staurosporine
Identifiers
PMID41278951
PMCPMC12632748
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