Evidence map›Paper›PMID 41278901›Full record

ArticlebioRxiv : the preprint server for biology2025

A Comprehensive Structural and Functional Analysis of

Jack W Creagh, David C Reetz, Lily L Givens, Sarah A Coss, Rodolfo Bizarria, Jagdish Suresh Patel, Andre Rodrigues, F Marty Ytreberg, Paul A Rowley

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Jack W CreaghDepartment of Biological Sciences, University of Idaho, Moscow, Idaho, USA.
David C ReetzDepartment of Biological Sciences, University of Idaho, Moscow, Idaho, USA.
Lily L GivensDepartment of Biological Sciences, University of Idaho, Moscow, Idaho, USA.
Sarah A CossDepartment of Biological Sciences, University of Idaho, Moscow, Idaho, USA.
Rodolfo BizarriaDepartment of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
Jagdish Suresh PatelInstitute for Modeling Collaboration and Innovation, University of Idaho, Moscow, ID, 83844, USA.
Andre RodriguesDepartment of General and Applied Biology, São Paulo State University (UNESP), Institute of Biosciences, Rio Claro, São Paulo, Brazil.
F Marty YtrebergDepartment of Physics, University of Idaho, Moscow, ID, 83844, USA.
Paul A RowleyDepartment of Biological Sciences, University of Idaho, Moscow, Idaho, USA.ORCID 0000-0002-3590-5139

Funding

Women's health: interplay of maternal diet and key demographics on neurological health in the rural frontier and remote WestP20GM103408 · NIGMS · UNIVERSITY OF IDAHO · PI Scott A Minnich · 2012 to 2026
$59.8M
Sequence-structure-function relationships in human visual photopigmentsP20GM104420 · NIGMS · UNIVERSITY OF IDAHO · PI MILLER, CRAIG R · 2015 to 2024
$22.9M
NIGMS NIH HHS P20 GM103408NIGMS NIH HHS P20 GM104420
6 · The paper itself

Abstract

Antifungal killer toxins are cytotoxic proteins that have the potential to combat the growing threat of fungi to human health and agriculture. A lack of empirical tertiary structures has placed limitations on understanding their mechanisms of action and targeting of pathogens. AlphaFold and molecular dynamics simulations were used to create tertiary structure models of all canonical

Identifiers

PMID41278901
PMCPMC12637454

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.