Evidence map›Paper›PMID 41278729›Full record

ArticlebioRxiv : the preprint server for biology2025

Discovery of Novel Probiotic Species to Improve Infant Health.

Ran Lu, Nakyung Lee, Austin K Drake, Ryan P Fulton, Nader Shawky Abutaleb, Mohamed Seleem, David Noah Oakland, Monica P Garin-Laflam, Mihai Pop, Xin M Luo

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ran LuDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.
Nakyung LeeDepartment of Computer Science, University of Maryland, College Park, MD, USA.
Austin K DrakePediatric Inflammatory Bowel Disease, Carilion Clinic Children's Hospital, Roanoke, VA, USA.
Ryan P FultonPediatric Inflammatory Bowel Disease, Carilion Clinic Children's Hospital, Roanoke, VA, USA.
Nader Shawky AbutalebCenter for One Health Research, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.
Mohamed SeleemCenter for One Health Research, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.ORCID 0000-0003-0939-0458
David Noah OaklandDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.
Monica P Garin-LaflamPediatric Inflammatory Bowel Disease, Carilion Clinic Children's Hospital, Roanoke, VA, USA.
Mihai PopDepartment of Computer Science, University of Maryland, College Park, MD, USA.
Xin M LuoDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.ORCID 0000-0002-2809-5836

Funding

The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve HealthUL1TR003015 · NCATS · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, JOHNSTON, KAREN C. · 2019 to 2023
$20.3M
NCATS NIH HHS UL1 TR003015
6 · The paper itself

Abstract

Selecting an appropriate infant formula can be challenging for parents given the wide range of available options, which may lead to suboptimal choices or frequent switching. Our recent studies in mice demonstrated that the maternal microbiota-particularly Importance: Early-life nutrition shapes immune maturation, yet the microbial factors driving mucosal antibody responses remain poorly defined. Through integrated metagenomic and IgA profiling, this study identifies commensal taxa, particularly

Indexed as

Breastmilkformulainfant microbiomepathogen-specific IgAprobiotics

Identifiers

PMID41278729
PMCPMC12636598

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.