Evidence map›Paper›PMID 41278720›Full record

ArticlebioRxiv : the preprint server for biology2025

RNA polymerase II-TFIIE-TFIIH interface functions in transcription start site selection in

Pratik Basnet, Yunye Zhu, Irina O Vvedenskaya, Payal Arora, Staci Hammer, Brittany McVicar, Shawn Alex, Bryce E Nickels, Craig D Kaplan

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Pratik BasnetDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0003-2809-2536
Yunye ZhuDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0001-9503-7882
Irina O VvedenskayaDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, United States.
Payal AroraDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, United States.ORCID 0009-0005-1512-2777
Staci HammerDepartment of Chemistry, Loras College, Dubuque, Iowa.
Brittany McVicarDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, United States.
Shawn AlexDepartment of Biochemistry & Biophysics, Texas A&M University, College Station, Texas.
Bryce E NickelsDepartment of Genetics and Waksman Institute, Rutgers University, Piscataway, United States.ORCID 0000-0001-7449-8831
Craig D KaplanDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0002-7518-695X

Funding

Transcription: Mechanism and RegulationR35GM118059 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI NICKELS, BRYCE EDWARD · 2016 to 2025
$7.1M
Mechanisms of RNA Polymerase II transcriptionR35GM144116 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Craig Kaplan · 2022 to 2026
$3.4M
Mechanism and Regulation of RNA Polymerase II ElongationR01GM097260 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPLAN, CRAIG · 2011 to 2020
$3.3M
"Mechanisms of RNA Polymerase II initiation"R01GM120450 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPLAN, CRAIG · 2016 to 2019
$1.7M
High-Throughput Computing for Genomics and Bioinformatics ResearchS10OD028483 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEE, ADRIAN V · 2021 to 2021
$574k
NIGMS NIH HHS R01 GM097260NIGMS NIH HHS R01 GM120450NIGMS NIH HHS R35 GM118059NIGMS NIH HHS R35 GM144116NIH HHS S10 OD028483
6 · The paper itself

Abstract

During transcription initiation in

Identifiers

PMID41278720
PMCPMC12637456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.