Evidence map›Paper›PMID 41278697›Full record

ArticlebioRxiv : the preprint server for biology2025

Pervasive suppressors halt the spread of selfish

Ching-Ho Chang, Tyler Handler, Nick Fuda, Danielle Pascua, Taylar Mouton, Amanda M Larracuente

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Ching-Ho ChangDivision of Basic Sciences, Fred Hutchinson Cancer Center, United States.ORCID 0000-0001-9361-1190
Tyler HandlerDepartment of Biology, University of Rochester, United States.ORCID 0009-0000-8071-3294
Nick FudaDepartment of Biology, University of Rochester, United States.
Danielle PascuaDepartment of Biology, University of Rochester, United States.
Taylar MoutonDepartment of Biology, University of Rochester, United States.
Amanda M LarracuenteDepartment of Biology, University of Rochester, United States.ORCID 0000-0001-5944-5686

Funding

The evolutionary and functional genomics of satellite DNAR35GM119515 · NIGMS · UNIVERSITY OF ROCHESTER · PI Amanda Marie Larracuente · 2016 to 2026
$4.0M
NIGMS NIH HHS R35 GM119515
6 · The paper itself

Abstract

Meiotic drivers are selfish genetic elements that subvert Mendelian inheritance to increase their own transmission, yet they are typically found at low frequencies across natural populations. The factors that limit their spread remain unclear. To investigate this paradox, we studied the

Indexed as

Drosophila Genetic Reference Panelmeiotic drivenatural variationSegregation Distorter

Identifiers

PMID41278697
PMCPMC12633045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.