Evidence map›Paper›PMID 41278678›Full record

ArticlebioRxiv : the preprint server for biology2025

Glypican-1 upregulation elicited in response to a cell-impermeable kinase inhibitor and its overexpression enhance HIV-1 infection.

Kelsey Vinzant, Natalia Cheshenko, Heng Pan, Ronald Cutler, Joshua N Buckler, Andreas Luxenburger, Lawrence D Harris, Jeffrey R Johnson, Steven C Almo, Betsy C Herold

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kelsey VinzantDepartment of Microbiology-Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Natalia CheshenkoDepartment of Pediatrics, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Heng PanDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Ronald CutlerDepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Joshua N BucklerFerrier Research Institute, Victoria University of Wellington, Wellington, New Zealand.
Andreas LuxenburgerFerrier Research Institute, Victoria University of Wellington, Wellington, New Zealand.
Lawrence D HarrisFerrier Research Institute, Victoria University of Wellington, Wellington, New Zealand.
Jeffrey R JohnsonDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Steven C AlmoDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Betsy C HeroldDepartment of Microbiology-Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America.ORCID 0000-0001-9974-0786

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI Ulrich Steidl · 1985 to 2026
$111.2M
Bigfoot Multispectral High Speed Fluorescence Activated Cell SorterS10OD032169 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI PORCELLI, STEVEN A · 2022 to 2022
$600k
Cytek Aurora Multiparameter Flow CytometerS10OD026833 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI PORCELLI, STEVEN A · 2019 to 2019
$367k
NCI NIH HHS P30 CA013330NIH HHS S10 OD026833NIH HHS S10 OD032169
6 · The paper itself

Abstract

Studies of herpes simplex virus (HSV) entry uncovered a previously unappreciated "outside-in" signaling pathway whereby activation of the calcium (Ca

Identifiers

PMID41278678
PMCPMC12636616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.