Evidence map›Paper›PMID 41278668›Full record

ArticlebioRxiv : the preprint server for biology2025

Developmental CA2 perineuronal net reduction restores social memory in

Emma J Diethorn, Aarushi B Rathaur, Brayan R Ruiz Lopez, Chino K Eke, Elizabeth Gould

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Emma J DiethornPrinceton Neuroscience Institute, Princeton University, Princeton NJ 08540.
Aarushi B RathaurPrinceton Neuroscience Institute, Princeton University, Princeton NJ 08540.
Brayan R Ruiz LopezPrinceton Neuroscience Institute, Princeton University, Princeton NJ 08540.
Chino K EkePrinceton Neuroscience Institute, Princeton University, Princeton NJ 08540.
Elizabeth GouldPrinceton Neuroscience Institute, Princeton University, Princeton NJ 08540.

Funding

Perineuronal nets, hippocampal plasticity, and autism spectrum disorder.R01MH118631 · NIMH · PRINCETON UNIVERSITY · PI Elizabeth Gould · 2019 to 2026
$3.1M
NIMH NIH HHS R01 MH118631
6 · The paper itself

Abstract

Individuals with Autism Spectrum Disorder (ASD) and related neurodevelopmental conditions, like Phelan-McDermid syndrome (PMDS), exhibit social recognition deficits. Previous reports using

Identifiers

PMID41278668
PMCPMC12632763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.