ReviewPublic health reviews2025
Biological Mechanisms Linking Social Adversity and Cognition.
Review in Public health reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Associations of Social Support, Loneliness, and Physical Activity with Cognitive Function in Older Adults with Mild Cognitive Impairment.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Various studies have shown that social adversity, such as loneliness or low SES, are linked with worse cognitive outcomes, though underlying biological mechanisms remain unclear. This scoping review aims to summarize existing evidence on biological processes that may serve as mediators underlying this association. Methods: Following PRISMA-ScR guidelines, studies measuring social adversity, cognition, and at least one biological mechanism were included. Results were summarized narratively and in tabular formats. Results: Twelve studies (n = 12) examined links between social adversity, cognition, and biological mechanisms. Inflammation, allostatic load, genetics and genetic aging markers were the three main biological mechanisms identified as potential mediators. Conclusion: Several studies suggest that these biological mechanisms may mediate the link between social adversity and cognitive decline. However, further research is needed to clarify these complex relationships, which are crucial for developing targeted interventions, especially for socially disadvantaged populations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.