Evidence map›Paper›PMID 41278458›Full record

ReviewEnvironmental science and ecotechnology2025

Immunoproteomics for wastewater-based health surveillance: A review.

Jaxaira Maggi, Joaquin Abian, Antoni Ginebreda, Damià Barceló, Montserrat Carrascal

Abstract readReview
In one paragraph

Review in Environmental science and ecotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jaxaira MaggiBiological and Environmental Proteomics, Institute of Biomedical Research of Barcelona, Spanish National Research Council (IIBB-CSIC/IDIBAPS), Roselló 161, 08036, Barcelona, Spain.
Joaquin AbianBiological and Environmental Proteomics, Institute of Biomedical Research of Barcelona, Spanish National Research Council (IIBB-CSIC/IDIBAPS), Roselló 161, 08036, Barcelona, Spain.
Antoni GinebredaInstitute of Environmental Assessment and Water Studies (IDAEA-CSIC), Department of Environmental Chemistry, Jordi Girona 18-26, 08034, Barcelona, Spain.
Damià BarcelóChemistry and Physics Department, University of Almería, 04120, Almería, Spain.
Montserrat CarrascalBiological and Environmental Proteomics, Institute of Biomedical Research of Barcelona, Spanish National Research Council (IIBB-CSIC/IDIBAPS), Roselló 161, 08036, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wastewater-based epidemiology (WBE) offers a unique window into the health and habits of communities through the analysis of pollutants and biomarkers in sewage. Traditionally focused on small molecules, such as pharmaceuticals and illegal drugs, recent advances in environmental proteomics have expanded WBE to include large biomolecules such as proteins. Notably, novel sampling methods using polymeric probes and high-resolution mass spectrometry have facilitated the detection of human and animal proteins, both soluble and in particulate material, linking them to specific populations and industrial activities. An immunological dimension to this approach is fundamental to include the recognition of host immunoglobulins, immune-response proteins, and pathogen antigens in wastewater, potentially serving as indicators of community immune status, infection prevalence, and vaccination coverage. This review consolidates the latest advancements in environmental proteomics as applied to WBE, emphasizing an immunological perspective as a comprehensive tool for assessing population health and environmental conditions to bridge environmental monitoring, public health, and clinical diagnostics.

Indexed as

ImmunoproteomicsMass spectrometryWastewater-based epidemiology

Identifiers

PMID41278458
PMCPMC12637087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.