Evidence map›Paper›PMID 41278393›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2025

Implementation of a High-Sensitivity Troponin Assay and Its Association With Resource Utilization in Patients With Suspected Acute Coronary Syndrome.

Radhika K Neicheril, Yosef Manla, Daniel Chacon, Kaylee Sarna, Alice Sonnino, Jared Piotrkowski, Kevin Perry, David Snipelisky

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Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Radhika K NeicherilDepartment of Cardiology, Section of Heart Failure & Cardiac Transplant Medicine, Cleveland Clinic Florida, Weston, FL.
Yosef ManlaDepartment of Cardiology, Section of Heart Failure & Cardiac Transplant Medicine, Cleveland Clinic Florida, Weston, FL.
Daniel ChaconDepartment of Internal Medicine, Cleveland Clinic Florida, Weston, FL.
Kaylee SarnaCenter for Clinical Research, Cleveland Clinic Foundation, Cleveland Clinic Florida, Weston, FL.
Alice SonninoDepartment of Internal Medicine, Cleveland Clinic Florida, Weston, FL.
Jared PiotrkowskiDepartment of Internal Medicine, Cleveland Clinic Florida, Weston, FL.
Kevin PerryDepartment of Internal Medicine, Cleveland Clinic Florida, Weston, FL.
David SnipeliskyDepartment of Cardiology, Section of Heart Failure & Cardiac Transplant Medicine, Cleveland Clinic Florida, Weston, FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine the association between the implementation of high-sensitivity cardiac troponin (hs-cTn) and downstream resource utilization in patients presenting to the emergency department (ED) with suspected acute coronary syndrome (ACS). Patients and Methods: We analyzed 461 ED encounters of patients with suspected ACS between January 1, 2022 and December 12, 2022. The final propensity score-matched analysis included 300 encounters in which the conventional cardiac troponin (c-cTn) assay (n=150) or hs-cTn assay (n=150) was used. Groups were compared for downstream resource utilization, including cardiology consults, cardiovascular imaging, disposition of care, ED length of stay, and 30-day outcomes, using appropriate statistical testing. Results: Compared with the c-cTn group, the hs-cTn group had a lower rate of requiring cardiology consults (6 [4%] vs 45 [30%]; Conclusion: Implementing hs-cTn in the ED can significantly reduce downstream testing and hospital resource utilization. Wider adoption of hs-cTn assays could present an opportunity to optimize care of patients with suspected ACS.

Identifiers

PMID41278393
PMCPMC12639368

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