Evidence map›Paper›PMID 41278357›Full record

ArticleKidney international reports2025

Clinical Characteristics, Symptoms, and Long-Term Outcomes in Gitelman Syndrome.

Michiel L A J Wieërs, Lise Allard, Viola D'Ambrosio, Pedro Arango-Sancho, Jeroen H F de Baaij, Francesca Becherucci, Aurelia Bertholet-Thomas, Martine Besouw, Anne Blanchard, Martina Cacciapuoti and 38 more

Abstract read
In one paragraph

Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A novel variant ofAME case reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Michiel L A J WieërsDivision of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Lise AllardPediatric Nephrology Unit, Centre de Référence Maladies Rénales Rares Sorare, Bordeaux University Hospital, Bordeaux, France.
Viola D'AmbrosioUOC Nefrologia, Dialisi e Trapianto, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Pedro Arango-SanchoDepartment of Pediatric Nephrology, Hospital Sant Joan de Déu, Barcelona, Spain.
Jeroen H F de BaaijDepartment of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Francesca BecherucciNephrology and Dialysis Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
Aurelia Bertholet-ThomasPediatric Nephrology Unit, Hospices Civils de Lyon, Centre de référence Maladies Rénales Rares MAREGE - Filière ORKiD, Lyon, France.
Martine BesouwDepartment of Pediatric Nephrology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Anne BlanchardParis Cité University, Paris, France.
Martina CacciapuotiNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padova, Italy.
Vincenza CarboneDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio," University of Florence, Florence, Italy.
Elisabeth A CornelissenDepartment of Pediatric Nephrology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.
Federico DaffaraNephrology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, Spedali Civili Hospital, University of Brescia, Brescia, BS, Italy.
Jan DegenhardtDepartment II of Internal Medicine, University of Cologne, Koln, Nordrhein-Westfalen, Germany.
Olivier DevuystInstitute of Physiology, University of Zürich, Zürich, Switzerland.
Eiske DorresteijnDepartment of Pediatric Nephrology, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, The Netherlands.
Rhys EvansDepartment of Renal Medicine, London Tubular Centre, University College London Medical School, London, UK.
Lucile FigueresNephrology, Nantes University Hospital, CR2TI ITUN, Nantes, UK.
Marc FilaPediatric Nephrology Unit, Centre Hospitalier Universitaire Arnaud de Villeneuve-Université de Montpellier, Centre de Référence Maladies Rénales Rares Sorare, France.
Marica GilibertiDepartment of Precision and Regenerative Medicine and Ionian Area-Nephrology, Dialysis and Transplantation Unit, University of Bari "Aldo Moro", Bari, Italy.
Valentine GillionDivision of Nephrology, Cliniques universitaires Saint-Luc, UCLouvain Medical School, Brussels, Belgium.
Sophie HaumannDepartment of Pediatrics, Pediatric Nephrology, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Gerlineke Hawkins-van der CingelDepartment of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Pascal HouillierCentre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université Paris Cité, Paris, France.
Marguerite HureauxParis Cité University, Paris, France.
Felix KnaufCentre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université Paris Cité, Paris, France.
Bertrand KnebelmannAPHP, Service de Nephrologie, Hôpital Universitaire Necker, Université de Paris, Paris, France.
Martin KonradDepartment of General Pediatrics, University Hospital Münster, Münster, Germany.
Theresa KwonDepartment of Pediatric Nephrology, Hôpital Robert Debré, Assistance Publique Hôpitaux de Paris, Paris, France.
Sandrine LemoineDepartment of Nephrology, Edouard Herriot Hospital, Rare Disease Reference Center (MAREGE), ORKID Network, Lyon, France.
Germana LongoNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padova, Italy.
Tom NijenhuisDepartment of Nephrology, Research Institute of Medical Innovations, Radboud University Medical Centre, Nijmegen, The Netherlands.
Rik H G Olde EngberinkDivision of Nephrology, Department of Internal Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Hector Ríos DuroDepartment of Pediatric Nephrology, Vall d'Hebron Universitary Hospital, Barcelona, Spain.
Chloé SaadéDepartment of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
John A SayerFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Karl-Peter SchlingmannDepartment of Pediatric Nephrology, Hôpital Robert Debré, Assistance Publique Hôpitaux de Paris, Paris, France.
Thomas SimonDepartment of Pediatric Nephrology, University Hospital Toulouse, Toulouse, France.
Marijn M SpeeckaertDepartment of Nephrology, Ghent University Hospital, Ghent, Belgium.
Hai Liang TanPaediatric Nephrology, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.
Francesco TrepiccioneDepartment of Medical Translational Sciences, University of Campania "Luigi Vanvitelli,", Naples, Italy.
Rosa Vargas-PoussouReference Center of Rare Renal Disease of Children and Adults (MARHEA), Paris, France.
Faidra VeligrattiPaediatric Nephrology, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK.
Stephen B WalshDepartment of Renal Medicine, London Tubular Centre, University College London Medical School, London, UK.
Mahdi SalihDivision of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Pedro H Imenez SilvaDivision of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Ewout J HoornDivision of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Gitelman Survey Study

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gitelman syndrome (GS) is a rare inherited salt-losing tubulopathy with limited clinical data. Methods: Surveys were conducted with GS physicians in Europe and patients with GS in the Netherlands to compare findings with the general population. Results: Data from 587 patients (25% pediatric) across 13 countries showed 93% were genotyped, with 94% having variants in Conclusions: These findings provide new insights into GS, highlight disease burden, and suggest areas for future research.

Indexed as

geneticshypokalemiahypomagnesemiapatient-reported outcomestubulopathy

Identifiers

PMID41278357
PMCPMC12640036

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.