ArticleKidney international reports2025
Universal Exit-Site Antibiotic Prophylaxis Reduces Exit-Site Infections in Pediatric Peritoneal Dialysis.
Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Exit-Site Care in Pediatric Peritoneal Dialysis Patients: From Personal Preference to Clinical Evidence.Kidney international reports · 2025Article
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Data on exit-site antibiotic prophylaxis in children undergoing peritoneal dialysis (PD) is scarce. Methods: We conducted a prospective observational cohort study of pediatric patients (aged < 21 years) who received chronic PD 2 years before (preprophylaxis) and/or 3 years after (postprophylaxis) implementing universal exit-site antibiotic prophylaxis. Catheter and exit-site care remained unchanged. The primary outcomes were annualized rates of exit-site infection (ESI), tunnel infection (TI), and peritonitis. Results: Fifty-seven children (32 girls; 15.1 years, interquartile range: 9.2-17.2) were included. All, except 2 patients underwent automated PD. Thirty-nine and 42 subjects, respectively, received PD during the preprophylaxis and postprophylaxis periods with comparable clinical characteristics. The observation period was 110.0 patient-years. Thirty-seven and 5 patients from the postprophylaxis period received mupirocin and gentamicin, respectively. The annualized ESI or TI rate was significantly lower in the postprophylaxis group (0.17, 95% confidence interval [CI]: 0.07-0.30 vs. 0.46, 95% CI: 0.29-0.68 episodes/patient-yrs; Conclusion: Daily exit-site antibiotic prophylaxis prevents gram-positive ESI or TI and shortens hospital stays in children undergoing PD.
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