Evidence map›Paper›PMID 41278257›Full record

ArticleMagnetic resonance letters2025

Validity of the Gaussian phase distribution approximation for analysis of isotropic diffusion encoding applied to restricted diffusion in a cylinder.

Daniel Topgaard

Abstract read
In one paragraph

Article in Magnetic resonance letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Daniel TopgaardDepartment of Chemistry, Lund University, SE-22100 Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Gaussian phase distribution approximation enables analysis of restricted diffusion encoded by general gradient waveforms but fails to account for the diffraction-like features that may occur for simple pore geometries. We investigate the range of validity of the approximation by random walk simulations of restricted diffusion in a cylinder using isotropic diffusion encoding sequences as well as conventional single gradient pulse pairs and oscillating gradient waveforms. The results show that clear deviations from the approximation may be observed at relative signal attenuations below 0.1 for one-dimensional sequences with few oscillation periods. Increasing the encoding dimensionality and/or number of oscillations while extending the total duration of the waveform diminishes the non-Gaussian effects while preserving the low apparent diffusivities characteristic of restriction.

Indexed as

DiffusionNMRPorous mediaPulsed gradient spin echoTensor-valued encoding

Identifiers

PMID41278257
PMCPMC12640017

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.