Evidence map›Paper›PMID 41278248›Full record

ArticleArtificial intelligence review2026

Knowledge distillation and dataset distillation of large language models: emerging trends, challenges, and future directions.

Luyang Fang, Xiaowei Yu, Jiazhang Cai, Yongkai Chen, Shushan Wu, Zhengliang Liu, Zhenyuan Yang, Haoran Lu, Xilin Gong, Yufang Liu and 14 more

Abstract read
In one paragraph

Article in Artificial intelligence review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Domain-Adaptive Diagnosis of Lewy Body Disease with Transferability Aware Transformer.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Luyang Fang *Department of Statistics, University of Georgia, Athens, GA USA.
Xiaowei Yu *Department of Computer Science and Engineering, The University of Texas at Arlington, Arlington, TX USA.
Jiazhang CaiDepartment of Statistics, University of Georgia, Athens, GA USA.
Yongkai ChenDepartment of Statistics, Harvard University, Cambridge, MA USA.
Shushan WuDepartment of Statistics, University of Georgia, Athens, GA USA.
Zhengliang LiuSchool of Computing, University of Georgia, Athens, GA USA.
Zhenyuan YangSchool of Computing, University of Georgia, Athens, GA USA.
Haoran LuDepartment of Statistics, University of Georgia, Athens, GA USA.
Xilin GongDepartment of Statistics, University of Georgia, Athens, GA USA.
Yufang LiuDepartment of Statistics, University of Georgia, Athens, GA USA.
Terry MaSchool of Computer Science, Carnegie Mellon University, Pittsburgh, PA USA.
Wei RuanSchool of Computing, University of Georgia, Athens, GA USA.
Ali AbbasiDepartment of Computer Science, Vanderbilt University, Nashville, TN USA.
Jing ZhangDepartment of Computer Science and Engineering, The University of Texas at Arlington, Arlington, TX USA.
Tao WangDepartment of Statistics, University of Georgia, Athens, GA USA.
Ehsan LatifAI4STEM Education Center, University of Georgia, Athens, GA USA.
Wei LiuDepartment of Radiation Oncology, Mayo Clinic Arizona, Phoenix, AZ USA.
Wei ZhangSchool of Computer and Cyber Sciences, Augusta University, Augusta, GA USA.
Soheil KolouriDepartment of Computer Science, Vanderbilt University, Nashville, TN USA.
Xiaoming ZhaiAI4STEM Education Center, University of Georgia, Athens, GA USA.
Dajiang ZhuDepartment of Computer Science and Engineering, The University of Texas at Arlington, Arlington, TX USA.
Wenxuan ZhongDepartment of Statistics, University of Georgia, Athens, GA USA.
Tianming LiuSchool of Computing, University of Georgia, Athens, GA USA.
Ping MaDepartment of Statistics, University of Georgia, Athens, GA USA.

Funding

Collaborative Research: DMS/NIGMS 2: Novel machine-learning framework for AFMscanner in DNA-protein interaction detectionR01GM152814 · NIGMS · UNIVERSITY OF GEORGIA · PI Wenxuan Zhong · 2023 to 2026
$1.2M
NIGMS NIH HHS R01 GM152814
6 · The paper itself

Abstract

The exponential growth of Large Language Models (LLMs) continues to highlight the need for efficient strategies to meet ever-expanding computational and data demands. This survey provides a comprehensive analysis of two complementary paradigms: Knowledge Distillation (KD) and Dataset Distillation (DD), both aimed at compressing LLMs while preserving their advanced reasoning capabilities and linguistic diversity. We first examine key methodologies in KD, such as task-specific alignment, rationale-based training, and multi-teacher frameworks, alongside DD techniques that synthesize compact, high-impact datasets through optimization-based gradient matching, latent space regularization, and generative synthesis. Building on these foundations, we explore how integrating KD and DD can produce more effective and scalable compression strategies. Together, these approaches address persistent challenges in model scalability, architectural heterogeneity, and the preservation of emergent LLM abilities. We further highlight applications across domains such as healthcare and education, where distillation enables efficient deployment without sacrificing performance. Despite substantial progress, open challenges remain in preserving emergent reasoning and linguistic diversity, enabling efficient adaptation to continually evolving teacher models and datasets, and establishing comprehensive evaluation protocols. By synthesizing methodological innovations, theoretical foundations, and practical insights, our survey charts a path toward sustainable, resource-efficient LLMs through the tighter integration of KD and DD principles.

Indexed as

Dataset distillationEfficiencyKnowledge distillationLarge language modelsModel compressionSurvey

Identifiers

PMID41278248
PMCPMC12634706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.