Evidence map›Paper›PMID 41278217›Full record

ArticleSleep advances : a journal of the Sleep Research Society2025

Cognitive behavioral therapy for insomnia as a suicide prevention strategy: a protocol for a systematic review and meta-analysis.

Cagdas Türkmen, Carlotta L Schneider, Yuki Furukawa, Jens H van Dalfsen, William V McCall, Wilfred R Pigeon, Andrew S Tubbs, Michael L Perlis, Dieter Riemann, Kai Spiegelhalder and 3 more

Abstract read
In one paragraph

Article in Sleep advances : a journal of the Sleep Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Reflecting on 2025. Anticipating 2026.Sleep advances : a journal of the Sleep Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cagdas TürkmenDepartment of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.ORCID https://orcid.org/0000-0003-1147-612X
Carlotta L SchneiderFaculty of Medicine, Department of Psychiatry, University of Geneva, Geneva, Switzerland.
Yuki FurukawaTechnical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, Munich, Germany.
Jens H van DalfsenDepartment of Psychiatry, University Medical Center Groningen, Groningen, The Netherlands.
William V McCallDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, GA, United States.ORCID https://orcid.org/0000-0001-5035-7858
Wilfred R PigeonDepartment of Psychiatry, University of Rochester Medical Center, Rochester, NY, United States.ORCID https://orcid.org/0000-0002-5753-7840
Andrew S TubbsDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.ORCID https://orcid.org/0000-0003-3799-5972
Michael L PerlisBehavioral Sleep Medicine Program, Department of Psychiatry, The School of Nursing, University of Pennsylvania, Philadelphia, PA, United States.
Dieter RiemannDepartment of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Kai SpiegelhalderDepartment of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Knut LangsrudØstmarka Psychiatric Department, St. Olavs Hospital PH, Trondheim, Norway.
Håvard KallestadDepartment for Research and Development, St. Olavs Hospital PH, Trondheim, Norway.ORCID https://orcid.org/0000-0002-9173-942X
Elisabeth HertensteinFaculty of Medicine, Department of Psychiatry, University of Geneva, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insomnia is a prevalent and debilitating sleep-wake disorder, with growing evidence indicating that it is an independent risk factor for suicidal ideation and behaviors. Cognitive behavioral therapy for insomnia is the recommended first-line treatment for chronic insomnia. However, its effect on suicidal ideation and behaviors in those with insomnia has not been well-characterized. Thus, the aim of the planned meta-analysis is to quantify the effects of cognitive behavioral therapy for insomnia on suicidal ideation, suicidal behaviors, and suicide deaths in adults with insomnia with and without comorbidities. This study will include randomized controlled trials comparing cognitive behavioral therapy for insomnia with a control condition with no presumed strong effect on insomnia in individuals with insomnia according to standardized diagnostic criteria or a clinically relevant screening score. Both published and unpublished randomized controlled trials will be retrieved through a systematic search in major databases and trial registries. The primary outcomes include suicidal ideation, suicidal behaviors, and suicide deaths, assessed post-treatment and at follow-ups. We will only consider randomized controlled trials reporting suicide-related outcomes and/or enrolling participants with suicidal ideation or behaviors. For continuous data, a random-effects meta-analysis will be conducted to estimate (standardized) mean differences. In the case of categorical data, a random-effects logistic regression meta-analysis model will be used. The risk of bias of the primary outcomes will be evaluated using the Cochrane Risk of Bias 2 tool. The certainty of evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluation framework.

Indexed as

CBT-Icognitive behavioral therapyinsomniasleep–wake disordersuicidalitysuicide

Identifiers

PMID41278217
PMCPMC12640200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.