ReviewFrontiers in cell and developmental biology2025
Plant-derived extracellular vesicles: an alternative and complementary therapeutic approach for genitourinary tumors.
Review in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Past, Present, and Future of Plant-Derived Extracellular Vesicles in Biomedical Applications.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Plant-Derived Nanocarriers for Drug Delivery: A Unified Framework Integrating Extracellular Vesicles, Engineered Phytocarriers, Hybrid Platforms, and Bioinspired Systems.Plants (Basel, Switzerland) · 2026Review
- Research advances in extracellular vesicles for diagnosis and treatment of genitourinary cancers.Frontiers in cell and developmental biology · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past four decades, the incidence of genitourinary tumors has risen significantly, becoming a major global health concern. This trend necessitates the exploration of more effective treatment strategies. Although considerable progress has been made in treatments such as endocrine, immune, and targeted therapies, these malignancies often remain uncontrolled, especially when metastatic. Recent advances in nanobiomedicine have revealed plant-derived extracellular vesicles as a novel and promising anti-cancer therapeutic option. These natural nanoparticles exhibit high biocompatibility, targeted delivery capability, and renewable properties, positioning them at the forefront of innovative cancer treatment strategies. Their inherent anti-cancer properties-such as inducing cell cycle arrest, promoting apoptosis, and inhibiting metastasis-may offer new alternatives for treating genitourinary cancers. This review summarizes current research on plant-based treatments for genitourinary tumors, focusing on the potential mechanisms and applications of plant-derived extracellular vesicles, thereby suggesting new nanoscale alternative and complementary therapeutic avenues.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.