Evidence map›Paper›PMID 41278158›Full record

ArticleWorld journal of gastroenterology2025

Reduced recurrence rate with a targeted approach in uncomplicated appendicitis treated with endoscopic direct

Jun Cai, Yang-Bor Lu, Yang Lv, Xiao-Juan Zhan, Ting Li, Guang Yang, Yu-Tong Ma, Jian-Zhen Ren, Bo Li, Heng Yu and 7 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Jun CaiDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Yang-Bor LuDepartment of Digestive Disease, Xiamen Chang Gung Hospital, Hua Qiao University, Xiamen 361028, Fujian Province, China.
Yang LvDepartment of Gastroenterology, Shenzhen Hospital of Southern Medical University, Shenzhen 510086, Guangdong Province, China.
Xiao-Juan ZhanDepartment of Digestive Disease, Xiamen Chang Gung Hospital, Hua Qiao University, Xiamen 361028, Fujian Province, China.
Ting LiDepartment of Gastroenterology, The First People's Hospital of Yunnan Province, Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, Yunnan Province, China.
Guang YangDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Yu-Tong MaDepartment of Gastroenterology, The First People's Hospital of Yunnan Province, Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, Yunnan Province, China.
Jian-Zhen RenDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Bo LiDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Heng YuDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Su-Huan LiaoDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Yi-Tian GuoDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Qiu-Ping QiuDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Xiao-Ping HongDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Long-Bin HuangDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China.
Yu ZhangDepartment of Gastroenterology, The First People's Hospital of Yunnan Province, Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, Yunnan Province, China.
Si-Lin HuangDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, Guangdong Province, China. silinhuang@szu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic retrograde appendicitis therapy (ERAT) offers an appendix-preserving approach; however, visual and specificity challenges persist. Conversely, endoscopic direct appendicitis therapy (EDAT) provides direct visual observation with diagnostic and therapeutic capabilities.

aimTo assess the efficacy and feasibility of EDAT and compare them with those of ERAT in uncomplicated appendicitis.

methodsIn this retrospective cohort study, patients diagnosed with uncomplicated appendicitis and treated with ERAT or EDAT between January 2021 and November 2024 were reviewed. The primary outcome was intervention success. Secondary outcomes were guidewire use, stent placement, hospitalization duration, recurrence, and endoscopic direct-view features. Outcomes were compared between groups

resultsOf 170 patients, 136 underwent EDAT and 34 ERAT. EDAT showed higher intervention success than ERAT (99.3%

conclusionEDAT was demonstrated to be a more effective and feasible approach than ERAT, with a lower overall cumulative recurrence risk and within the appendicolith subgroup. Consistent results after PSM further supported the robustness of these findings.

Indexed as

AppendectomyAppendicitisAdultFeasibility StudiesFemaleHumansLength of StayMaleMiddle AgedPropensity ScoreRecurrenceRetrospective StudiesSecondary PreventionStentsTreatment OutcomeYoung AdultAppendicographyAppendicolithAppendicoscopeDiagnosisEndoscopic direct appendicitis therapyEndoscopic retrograde appendicitis therapyFecalithNegative appendectomyUncomplicated appendicitis

Identifiers

PMID41278158
PMCPMC12635755

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.