Evidence map›Paper›PMID 41277992›Full record

ArticleMethodsX2025

Phantom design for tracked ultrasound-based surgical navigation systems.

V J van Boheemen, J M van der Zee, M Kuipers, M Fitski, M H W A Wijnen, F J Siepel, A F W van der Steeg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MethodsX, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Performance of a tracked ultrasound navigation setup for pediatric tumor surgery: a phantom study.International journal of computer assisted radiology and surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

V J van BoheemenPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, Utrecht 3584 CS, the Netherlands.
J M van der ZeePrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, Utrecht 3584 CS, the Netherlands.
M KuipersRobotics and Mechatronics, University of Twente, Hallenweg 15, Enschede 7522NH, the Netherlands.
M FitskiPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, Utrecht 3584 CS, the Netherlands.
M H W A WijnenPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, Utrecht 3584 CS, the Netherlands.
F J SiepelRobotics and Mechatronics, University of Twente, Hallenweg 15, Enschede 7522NH, the Netherlands.
A F W van der SteegPrincess Maxima Center for Pediatric Oncology, Heidelberglaan 25, Utrecht 3584 CS, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For pediatric oncology patients, radical tumor removal is crucial. Surgical navigation using tracked ultrasound may improve radical removal rates in pediatric surgery, based on positive clinical outcomes in adult tumor surgery. Prior to implementation, such surgical navigation systems must be validated under controlled conditions. This requires surgical phantoms with a speed of sound comparable to human tissue to enable accurate tracked ultrasound imaging and which include anatomical structures with ultrasound and Computed Tomography (CT) contrast. However, scarcity exists of such phantoms. This study presents a method for developing anatomical phantoms tailored for evaluating tracked ultrasound-based surgical navigation systems.•A gelatin-vinegar matrix was selected for its speed of sound, durability and stability.•Tumors were developed using polyvinyl alcohol mixed with glass microspheres and barium sulfate to achieve ultrasound and CT contrast.The speed of sound of the gelatin-vinegar matrix was investigated by depth measurements on both ultrasound and CT imaging. The resulting phantoms are durable, low-cost (<50$ p/phantom) and have a speed of sound approximating human tissue to enable tracked ultrasound. Moreover, the phantom materials are widely available, and the phantoms are easy to make. With this protocol, we offer a method for preclinical validation of ultrasound-based surgical navigation systems.

Indexed as

Image guided surgeryPediatric oncology surgerySurgical phantom developmentTissue mimicking materialTracked ultrasound

Identifiers

PMID41277992
PMCPMC12637238

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.