Evidence map›Paper›PMID 41277855›Full record

ArticleApplied and environmental microbiology2025

The molecular basis of the synergistic toxicity of nickel and copper, common environmental co-contaminants.

Linda Darwiche, Carlos A Rodriguez-Bornot, Rebecca A Ingrassia, Max J Loccisano, Gray Waldschmidt, Jennifer L Goff

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linda DarwicheDepartment of Chemistry, SUNY College of Environmental Science and Forestry, Syracuse, New York, USA.ORCID 0009-0001-1612-3369
Carlos A Rodriguez-BornotDepartment of Environmental Biology, SUNY College of Environmental Science and Forestry, Syracuse, New York, USA.ORCID 0009-0004-8868-890X
Rebecca A IngrassiaDepartment of Environmental Biology, SUNY College of Environmental Science and Forestry, Syracuse, New York, USA.
Max J LoccisanoDivision of Environmental Science, SUNY College of Environmental Science and Forestry, Syracuse, New York, USA.
Gray WaldschmidtDepartment of Sustainable Resources Management, SUNY College of Environmental Science and Forestry, Syracuse, New York, USA.
Jennifer L GoffDepartment of Chemistry, SUNY College of Environmental Science and Forestry, Syracuse, New York, USA.ORCID 0000-0002-9089-9632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy metals are ubiquitous in the environment due to both natural processes and anthropogenic activities. Nickel (Ni) and copper (Cu) commonly co-occur in contaminated environments, yet most toxicity studies focus on individual metals. We investigated the combined toxicity of Ni and Cu in

Indexed as

CopperEnvironmental PollutantsEscherichia coliNickelDrug SynergismEscherichia coli ProteinsGene Expression Regulation, BacterialSulfurCopperEnvironmental PollutantsEscherichia coli ProteinsNickelSulfurmetabolomicsmetalsstresstranscriptomics

Identifiers

PMID41277855
PMCPMC12724342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.