Evidence map›Paper›PMID 41277819›Full record

ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2026

To Bleach or Not to Bleach?-The Role of Bleaching in the Clinical Workflow for the Treatment of Demarcated Opacities in Anterior Teeth.

Linda Greenwall, Marcus Cebula, Joseph Greenwall-Cohen, Falk Schwendicke, Susanne Effenberger

Abstract readCase Reports
In one paragraph

Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linda GreenwallGreenwall Dental, London, UK.
Marcus CebulaClinical Research, Dental-Material Gesellschaft mbH, Hamburg, Germany.ORCID https://orcid.org/0000-0002-0149-1580
Joseph Greenwall-CohenGreenwall Dental, London, UK.
Falk SchwendickeDepartment of Conservative Dentistry, Periodontology and Digital Dentistry, LMU Klinikum, LMU Munich, Munich, Germany.ORCID https://orcid.org/0000-0003-1223-1669
Susanne EffenbergerClinical Research, Dental-Material Gesellschaft mbH, Hamburg, Germany.ORCID https://orcid.org/0000-0001-7994-2444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo present a structured, stepwise approach for the esthetic management of demarcated anterior opacities associated with molar-incisor hypomineralization (MIH), emphasizing the role of bleaching within a minimally invasive treatment workflow. CLINICAL CONSIDERATIONS: Discoloration of anterior teeth, particularly MIH-related opacities, can significantly affect Psychosocial well-being and overall health. Recommended interventions range from non-invasive and microinvasive techniques, such as bleaching and resin infiltration, to more invasive options like composite restorations. Due to the variability in opacities, a combination of treatment modalities is often necessary. From a clinical workflow perspective, MIH-affected anterior teeth can be categorized into basic, advanced, and complex cases, depending on their appearance and anticipated treatment needs. This clinical report demonstrates the proposed stepwise approach in five cases: two basic, two advanced, and one complex, illustrating how complexity guides treatment selection.

conclusionA minimally invasive approach should be prioritized for managing MIH-related anterior discolorations. Bleaching serves as an important first-line option before considering more invasive alternatives, thereby preserving hard tooth structure-an especially critical consideration in pediatric patients. CLINICAL SIGNIFICANCE: Implementing a systematic, minimally invasive treatment protocol for MIH-affected anterior teeth can enhance esthetic outcomes while maintaining tooth integrity, thereby improving patient confidence, identity and quality of life.

Indexed as

Dental Enamel HypoplasiaTooth BleachingTooth Bleaching AgentsAdolescentChildEsthetics, DentalFemaleHumansIncisorMaleWorkflowTooth Bleaching Agentsbleachingdemarcated opacitiesdevelopmental defects of the enamelMIHOHRQoLpediatric dentistryresin infiltration

Identifiers

PMID41277819
PMCPMC13062725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.