Evidence map›Paper›PMID 41277771›Full record

ArticleJournal of proteome research2025

Storing Mass-Spectrometry Data in Simple Databases Enables Flexible and Intuitive Exploration without Time or Space Penalties.

William Kumler, Sam LaRue, Anitra E Ingalls

Abstract read
In one paragraph

Article in Journal of proteome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William KumlerSchool of Oceanography, University of Washington, 1501 NE Boat St, Seattle, Washington 98195, United States.ORCID 0000-0002-5022-8009
Sam LaRueDepartment of Mechanical Engineering, University of Washington, 3900 E Stevens Way NE, Seattle, Washington 98195, United States.
Anitra E IngallsSchool of Oceanography, University of Washington, 1501 NE Boat St, Seattle, Washington 98195, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mass spectrometry (MS) generates large data sets that are stored in increasingly optimized and complex file types, demanding technical expertise to extract information rapidly and easily. We wondered whether a simple structured query language (SQL) database could hold raw MS data and allow for easily readable queries without incurring major penalties in the read time or disk space relative to other popular MS formats. Here, we describe a basic MS schema with intuitive database tables and fields that can outperform other formats for exploratory and interactive analysis according to six data subsets commonly extracted: single scans (both MS

Indexed as

Databases, FactualDatabases, ProteinInformation Storage and RetrievalMass SpectrometrySoftwarebenchmarkingdata storageexploratory data analysishuman-centered designliquid chromatographymass spectrometrySQL

Identifiers

PMID41277771
PMCPMC12687358

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.