Evidence map›Paper›PMID 41277588›Full record

ArticleInternational journal of cancer2026

Impact of lung cancer screening eligibility criteria on participants' characteristics and healthcare resources.

María Olivia Cabrera, Kevin Ten Haaf, Josep Maria Borràs, Rebeca Font, Judit Solà, Juul Hubert, Mónica Ballesteros, Josep Alfons Espinàs

Abstract read
In one paragraph

Article in International journal of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

María Olivia CabreraBellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.ORCID https://orcid.org/0009-0006-6530-1877
Kevin Ten HaafDepartment of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0001-5006-6938
Josep Maria BorràsBellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
Rebeca FontCatalonian Cancer Strategy, Department of Health, Barcelona, Spain.
Judit SolàCatalonian Cancer Strategy, Department of Health, Barcelona, Spain.
Juul HubertDepartment of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands.
Mónica BallesterosCatalonian Cancer Strategy, Department of Health, Barcelona, Spain.
Josep Alfons EspinàsBellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.

Funding

Departament de Recerca i Universitats de la Generalitat de Catalunya 2021 SGR 00808European Union Horizon 2020 848294
6 · The paper itself

Abstract

Selection criteria for lung cancer screening (LCS) are essential for implementing resource- and cost-efficient programs. However, different selection criteria may have similar resource requirements but select dissimilar individuals. This study explores the impact of inclusion criteria on participants' characteristics and health services in Spain. A cross-sectional study was conducted using data from 21,007 individuals from the 2012 Spanish National Health Survey. LCS eligibility was evaluated for four criteria: two from the 4-IN-THE-LUNG-RUN trial (4ITLR1: ages 60-79, 35 pack-years, current smokers or <10 years since cessation; 4ITLR2: ages 60-79, PLCOm2012noRace risk ≥2.6%), the United Kingdom's Targeted Lung Health Check (TLHC: ages 55-74, PLCOm2012noRace risk ≥1.51%), and the United States Preventive Services Task Force (USPSTF: ages 50-80, 20 pack-years, current smokers or <15 years since cessation). Under the most restrictive (4ITLR1) 5.6% of ages 50-80 were eligible, requiring 9.0% additional radiological capacity. Under the broadest (USPSTF) 21.6% of ages 50-80 were eligible, requiring 34.2% additional capacity. All criteria primarily selected men (68.1-82.2% of eligibles). Most criteria favored selecting former smokers (49.4-56.9%). However, eligible women were more often current smokers than men across all criteria (men: 38.5-46.8%, women: 52.7-66.5%). Former smokers smoked more cigarettes per day than current smokers (30 vs. 20) despite having shorter smoking durations, resulting in higher median pack-years across all criteria (range: 44-66). Overall, pack-year-based eligibility decreased with age, while risk-based eligibility was stable across age groups. Different LCS criteria yield populations with highly varied characteristics. Risk-based criteria may provide more equitable eligibility across age groups.

Indexed as

Early Detection of CancerEligibility DeterminationHealth ResourcesLung NeoplasmsPatient SelectionAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedSpaineligibility criteriahealth services impactlung cancer screeningrisk prediction modelsscreening strategies

Identifiers

PMID41277588
PMCPMC12963714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.