Evidence map›Paper›PMID 41277308›Full record

ArticleJournal of applied clinical medical physics2025

Dosimetric characterization of a Varex VF-80/μXHP x-ray unit using open-ended applicators for superficial radiotherapy.

Muhammad Zeeshan, Yikai Wu, Zhongyu Qi, Ning Gao, Xi Pei, Xie George Xu

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muhammad ZeeshanSchool of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, China.ORCID https://orcid.org/0009-0001-5830-0896
Yikai WuSchool of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, China.
Zhongyu QiSchool of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, China.
Ning GaoSchool of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, China.
Xi PeiSchool of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, China.
Xie George XuSchool of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, China.

Funding

Alliance of National and International Science Organizations for Belt and Road Regions (ANSO)Anhui Province Key Research and Development Plan 2023s07020020Development of Medical Physics and Biomedical Engineering Interdisciplinary Subjects YD2140000601National Natural Science Foundation of China 12275372
6 · The paper itself

Abstract

backgroundKilovoltage x-ray units (50-150 kVp) are widely used for skin cancer treatments, necessitating precise dosimetric characterization to ensure accurate dose delivery. This study validates the depth dose data of the VF-80/𝜇XHP (80 kV, 100 W) x-ray system for use in low-kV therapy with a contemporary detector.

objectiveThis research aims to characterize the kilovoltage VF-80/𝜇XHP x-ray unit with open-ended PMMA and stainless-steel applicators of various diameters by utilizing different x-ray energy values.

methodsMeasurements included machine output reproducibility, applicator leakage and thickness effects, measurement of HVL, reference output dosimetry, and applicator-to-phantom spacing. PDD curves were obtained using various filter/kV and applicator combinations with a PTW 34013 parallel-plate ionization chamber in a solid water phantom and through MC simulations with the TOPAS Monte Carlo code in a water phantom, which were validated against literature data.

resultsThe study evaluated around 40 x-ray beams. The PDDs were measured in a solid water phantom using a PTW 34013 ionization chamber and calculated with the TOPAS Monte Carlo code. Both the measured and computed percent depth dose data were compared to the BJR 25 supplementary. The agreement between ionization chamber measurements and MC calculations with BJR 25 supplementary was within [1.9%, 1.5%] for 50 kV x-rays and within [0.5%, 0.2%] for 70 kV x-rays.

conclusionThis research provides the dosimetric analysis of a kilovoltage VF-80/μXHP x-ray machine. The primary focus was on using a PTW 34013 ionization chamber to measure the percentage depth dose in a solid water phantom, along with dose calculations performed using the TOPAS Monte Carlo simulation. The findings align well with existing literature, confirming that this x-ray unit is suitable for low-kV x-ray radiotherapy applications.

Indexed as

Particle AcceleratorsPhantoms, ImagingRadiometryRadiotherapy Planning, Computer-AssistedSkin NeoplasmsHumansMonte Carlo MethodRadiotherapy DosageRadiotherapy, Intensity-Modulatedionization chamberlow‐kV radiotherapyMonte Carlo simulationspercent depth dose

Identifiers

PMID41277308
PMCPMC12641097

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.