ArticleAngewandte Chemie (International ed. in English)2026
Pre-Activation as a Route for Tuning the Kinetics of Mechanochemical Transformations.
Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Force-Accelerated Autocatalysis in a Knoevenagel Condensation Reaction during Ball Milling.Journal of the American Chemical Society · 2026Article
- Scaling up mechanochemical reactions: linking crystalline phase evolution studiedChemical science · 2026Article
- Pre-Activation as a Route for Tuning the Kinetics of Mechanochemical Transformations.Angewandte Chemie (International ed. in English) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Learning to control reaction kinetics is essential for translating any chemical technology into real-world application. Based on time-resolved in situ powder X-ray diffraction data, we demonstrate the opportunity to tune mechanochemical reaction rates through the pre-activation of the starting reagents. For three model co-crystal systems, the pre-activation of the most stable reagent yields up to a ca 10-fold increase in the reaction rate, whilst negligible kinetic enhancement is seen when the less stable reagent is pre-activated. Moreover, we demonstrate how the polymorphic outcome of mechano-co-crystallization is also sensitive to pre-activation of the starting material. Our results suggest that reproducibility of mechanochemical processes requires detailed understanding over the origin and history of reagent powders, whilst providing a new conceptual framework to design and control mechanochemical reactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.