Evidence map›Paper›PMID 41277168›Full record

ArticleJournal of pediatric gastroenterology and nutrition2026

Dolichocolon is common in pediatric gastroenterology patients with constipation and associated complaints.

David Simon, Donovan Berens, Raul Zambrana Valenzuela, Arvind Mohan, Partha Chakraborty, Timot Kellermayer, Eric H Chiou, Craig L Jensen, Ricardo A Arbizu, Marla B K Sammer and 1 more

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Article in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

David SimonDivision of Pediatric Gastroenterology, Cardinal Glennon Children's Hospital, St. Louis University, St Louis, Missouri, USA.
Donovan BerensDivision of Pediatric Gastroenterology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Raul Zambrana ValenzuelaDepartment of Radiology, Baylor College of Medicine, Houston, Texas, USA.
Arvind MohanTexas College of Osteopathic Medicine, The University of North Texas Health Science Center, Fort Worth, Texas, USA.
Partha ChakrabortyDivision of Pediatric Gastroenterology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Timot KellermayerDepartment of Diagnostic and Interventional Imaging, McGovern Medical School, Houston, Texas, USA.
Eric H ChiouDivision of Pediatric Gastroenterology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Craig L JensenDivision of Pediatric Gastroenterology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Ricardo A ArbizuDivision of Pediatric Gastroenterology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Marla B K SammerDepartment of Radiology, Baylor College of Medicine, Houston, Texas, USA.
Richard KellermayerDivision of Pediatric Gastroenterology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.ORCID https://orcid.org/0000-0002-4146-1335

Funding

Gutsy Kids Fund
6 · The paper itself

Abstract

objectivesDolichocolon (DC), classified under International Classification of Diseases, Tenth Revision (ICD-10) code Q43.8 ("Other specified congenital malformations of intestine"), refers to an elongated or redundant large intestine. Recent studies in adults indicate a role for dolichocolon in constipation and disorders of gut-brain interaction. Contrast enema (CE) imaging is commonly used to identify DC, typically defined as a sigmoid colon extending above, or a transverse colon descending below, the iliac crest line. Despite its potential relevance, the prevalence and clinical significance of DC in pediatric gastroenterology remain poorly understood.

methodsThis retrospective study assessed the prevalence of DC in pediatric patients presenting with constipation and related gastrointestinal symptoms. A total of 155 contrast enemas from pediatric gastroenterology patients meeting predefined inclusion criteria were reviewed. Three blinded pediatric gastroenterologists independently evaluated each CE for features of colonic redundancy consistent with dolichocolon, based on a priori imaging criteria.

resultsConsensus-based identification (i.e., independent agreement among all three reviewers) of DC was observed in 74.1% of children under 2 years old and 88.6% of those aged 2-4 years presenting with constipation. The prevalence significantly decreased with age, with 68.8% in children aged 5-10 years and 47.6% in adolescents aged 11-17 years.

conclusionsThese findings suggest that dolichocolon is common in pediatric patients with constipation and relatable symptoms, particularly in early childhood. Further research is warranted to clarify its clinical implications and potential role in pediatric gastrointestinal disorders.

Indexed as

ColonConstipationAdolescentChildChild, PreschoolEnemaFemaleGastroenterologyHumansInfantMalePrevalenceRetrospective Studiesabdominal paincongenitalfecal retentionredundant colonvariant

Identifiers

PMID41277168
PMCPMC12864178

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.