Evidence map›Paper›PMID 41277036›Full record

ArticleAnnals of medicine2025

The clinical value of shear wave elastography on placental function in pregnant women with hypothyroidism in late pregnancy.

Xuan Gao, Zhi-Jun Zhang, Hai-Rong Zou, Min Xie, Xiao-Ya Ding, Wei Wang, Hui Wang

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Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Xuan GaoUltrasound Department of Chongqing Medical University Affiliated University City Hospital, Chongqing, China.
Zhi-Jun ZhangUltrasound Department of Chongqing Medical University Affiliated University City Hospital, Chongqing, China.ORCID 0000-0002-4800-0291
Hai-Rong ZouUltrasound Department of Chongqing Medical University Affiliated University City Hospital, Chongqing, China.
Min XieUltrasound Department of Chongqing Medical University Affiliated University City Hospital, Chongqing, China.ORCID 0009-0009-9955-8509
Xiao-Ya DingUltrasound Department of Chongqing Medical University Affiliated University City Hospital, Chongqing, China.
Wei WangUltrasound Department of Chongqing Medical University Affiliated University City Hospital, Chongqing, China.
Hui WangUltrasound Department of Chongqing Medical University Affiliated University City Hospital, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose of the work is to measure placental elasticity in pregnant women with hypothyroidism by shear wave elastography (SWE), and to evaluate the clinical value of SWE on placental function in pregnant women with hypothyroidism.

methodsIn total, 57 Hypothyroidism (Hypothyroidism group) and 74 normal control women (NC group) who received antenatal examination in our hospital from February 2024 to November 2024. Placental mean elasticity (E-mean), mean shear wave velocities (SWV-mean), uterine artery/umbilical arteries related parameters (UtA/UmbA-PI/RI/S/D) were measured. The pregnancy outcomes of pregnant women were followed up. The correlation between E-mean and preterm birth, uterine/umbilical artery parameters was analyzed. Meanwhile, the Receiver Operating Characteristic (ROC) curve was used to analyze the predictive power of E-mean on placental function.

resultsThere were significant difference in E-mean, SWV-mean,UtA -PI,UtA -RI,UtA -S/D between the Hypothyroidism group and the NC group (PE-mean/PSMV-mean/PUtA-PI/PUtA-RI/PtA-S/D=0.023/0.013/0.047/0.038/0.025).The most effective parameter for evaluating placental function was the E-mean (AUC = 0.86). E-mean was positively correlated with the incidence of preterm birth and UtA-PI, UtA- RI, UtA-S/D, but not significantly correlated with low-birth-weight infants and fetal distress. Compared with the NC group, pregnant women with hypothyroidism had a higher incidence of premature birth.

conclusionsThe hardness of the placenta could be quantitatively evaluated by SWE. E-mean was the most effective parameter for evaluating placental function in pregnant women with hypothyroidism during late pregnancy. Pregnant women with hypothyroidism had greater placental hardness and a higher incidence of premature birth.

Indexed as

Elasticity Imaging TechniquesHypothyroidismPlacentaPregnancy ComplicationsAdultCase-Control StudiesElasticityFemaleHumansPregnancyPregnancy OutcomePremature BirthROC CurveUmbilical ArteriesUterine Arteryelastic valuehypothyroidismplacentaplacental functionShear wave elastography

Identifiers

PMID41277036
PMCPMC12646085

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