Evidence map›Paper›PMID 41276990›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Enzyme-Inspired Hydrogen-Bonded Organic Frameworks for Synergistic Capture, Detection, and Degradation of Nerve Agent Simulants.

Jiabao Liu, Guanglai Mo, Xiangyu Gao, Yingjia Deng, Yijin Wang, Qingyu Niu, Yujie Lei, Bin Fei, Joanne Yip, Zhaozhen Zhang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Rapidly Diversifying Hydrogen-Bonded Organic Frameworks With Permanent Porosity.Angewandte Chemie (International ed. in English) · 2026
    Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jiabao LiuSchool of Chemical Engineering and Technology, Hebei University of Technology, Xiping Dao 5340, Beichen District, Tianjin, 300401, China.
Guanglai MoState Key Laboratory of Porous Materials for Separation and Conversion, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, College of Smart Materials and Future Energy, Fudan University, 2005 Songhu Road, Shanghai, 200438, China.
Xiangyu GaoState Key Laboratory of Porous Materials for Separation and Conversion, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, College of Smart Materials and Future Energy, Fudan University, 2005 Songhu Road, Shanghai, 200438, China.
Yingjia DengState Key Laboratory of Porous Materials for Separation and Conversion, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, College of Smart Materials and Future Energy, Fudan University, 2005 Songhu Road, Shanghai, 200438, China.
Yijin WangState Key Laboratory of Porous Materials for Separation and Conversion, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, College of Smart Materials and Future Energy, Fudan University, 2005 Songhu Road, Shanghai, 200438, China.
Qingyu NiuSchool of Chemical Engineering and Technology, Hebei University of Technology, Xiping Dao 5340, Beichen District, Tianjin, 300401, China.
Yujie LeiSchool of Fashion and Textiles, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR 999077, China.
Bin FeiSchool of Fashion and Textiles, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR 999077, China.
Joanne YipSchool of Fashion and Textiles, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR 999077, China.
Zhaozhen ZhangResearch Center of Green Catalysis, College of Chemistry, Zhengzhou University, Zhengzhou, 450001, China.
Jie WuResearch Center of Green Catalysis, College of Chemistry, Zhengzhou University, Zhengzhou, 450001, China.
Yunbo BiState Key Laboratory of Porous Materials for Separation and Conversion, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, College of Smart Materials and Future Energy, Fudan University, 2005 Songhu Road, Shanghai, 200438, China.
Kaikai MaSchool of Fashion and Textiles, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR 999077, China.
Zhiqiang LiSchool of Chemical Engineering and Technology, Hebei University of Technology, Xiping Dao 5340, Beichen District, Tianjin, 300401, China.
Peng LiState Key Laboratory of Porous Materials for Separation and Conversion, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, College of Smart Materials and Future Energy, Fudan University, 2005 Songhu Road, Shanghai, 200438, China.ORCID https://orcid.org/0000-0002-4273-4577

Funding

Hong Kong Polytechnic University 1-BBCBHong Kong Polytechnic University 1-WZ2HHong Kong Research Grants Council CRF 3-RC53National Natural Science Foundation of China 22171069National Natural Science Foundation of China 22575053National Nature Science Foundation of China 22171069National Nature Science Foundation of China 22575053Natural Science Foundation of Hebei Province B2025202024Science and Technology Commission of Shanghai Municipality 2024ZDSYS02Science Research Project of Hebei Education Department JZX2024012Tianjin Natural Science Foundation 23JCYBJC00800
6 · The paper itself

Abstract

Nerve agents (NAs), a class of highly toxic organophosphorus (OP) compounds, pose a significant threat to global security. The development of integrated protective materials that can simultaneously capture airborne OPs, detect, and degrade them remains a formidable challenge. Inspired by lipase's specific binding to OPs, a biomimetic hydrogen-bonded organic framework (HOF) is developed, FDU-HOF-5. It achieves highly efficient and selective adsorption of a sarin simulant, diethyl chlorophosphate (DCP), by combining size exclusion with molecular recognition via specific N─P bond formation, effectively distinguishing DCP from various OP analogues. Upon adsorption, the material responds within 5 s, enabling bimodal identification via a visual color change (yellow to red) and a fluorescence signal (99.7% quenching, 75 nm redshift). The adsorbed DCP is then self-drivenly hydrolyzed into non-toxic products by environmental moisture, achieving 91.5% degradation efficiency. Utilizing the solution processability of HOFs, functional textiles that show an immediate color change upon DCP exposure are produced. This work establishes a rational design strategy for multifunctional HOF systems that synergistically integrate capture, detection, and degradation for effective threat mitigation.

Indexed as

hydrogen‐bonded organic frameworksinstantaneous capturenerve agent simulantsselective recognitionspontaneous degradation

Identifiers

PMID41276990
PMCPMC12884759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.