Evidence map›Paper›PMID 41276970›Full record

SynthesisJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

The Relationship Between Nasal Septal Deviation and Rhinosinusitis: A Systematic Review.

Aidan Shulkin, Alexandra Katz, Marc A Tewfik

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aidan ShulkinFaculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.ORCID 0009-0000-1525-0350
Alexandra KatzFaculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.ORCID 0000-0002-7137-6393
Marc A TewfikDepartment of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, Quebec, Canada.ORCID 0000-0002-2650-6013

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ImportanceNasal septal deviation (NSD) and rhinosinusitis (RS) are common conditions with overlapping symptoms, yet they require distinct treatment approaches. Clarifying their relationship is essential to guide preventative management strategies.ObjectiveTo examine the association between NSD and RS.DesignSystematic review following the PRISMA guidelines. Embase, MEDLINE, and Web of Science were searched from inception to January 2025.ParticipantsStudies were included if participants were adults (≥18 years); studies conducted exclusively in pediatric populations were excluded.Main Outcome MeasuresAssociation between NSD and RS based on prevalence, NSD severity, and mean nasal septal angle (NSA), as well as overall study quality and risk of bias.ResultsA total of 34 studies were included, of which 26 reported NSD and 8 reported RS as their primary outcome. Among the studies reporting on NSD, 17 assessed prevalence, of which 7 (41.2%) demonstrated an association with RS; 5 assessed severity, of which 2 (40.0%) demonstrated an association between moderate/severe NSD and RS; and 10 assessed mean NSA, of which 3 (30.0%) demonstrated an association with RS. All studies reporting on RS assessed prevalence, of which 4 (50.0%) demonstrated an association with NSD. Overall, 16/40 (40.0%) individual outcome measures indicated an association between NSD and RS. A risk of bias analysis identified 12/34 (35.3%) studies as low risk. Of these, 5/17 (29.4%) individual outcomes measures demonstrated an association between NSD and RS.ConclusionThe current body of evidence reveals an inconclusive relationship between NSD and RS. Variability in definitions, diagnostic criteria, and outcome measures, combined with insufficient control for bias, limit the ability to draw definitive conclusions.Relevance:We propose standardized reporting guidelines to ensure consistency across studies and enable more meaningful comparisons. Implementing this framework may ultimately support the development of preventative strategies to optimize patient outcomes.PROSPERO registration numberCRD42024514049.

Indexed as

Nasal SeptumNose Deformities, AcquiredRhinitisSinusitisHumansPrevalenceRhinosinusitisNasal septal deviationOtolaryngologyRhinologyRhinosinusitisSystematic review

Identifiers

PMID41276970
PMCPMC12644427

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.