Evidence map›Paper›PMID 41276916›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Bimetallic Peroxide Nanocomposites-Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy.

Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guanting HeKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China.
Haixia ZhuCancer Institute, Affiliated Tumor Hospital of Nantong University, Nantong, 226631, P. R. China.
Peipei KangCancer Institute, Affiliated Tumor Hospital of Nantong University, Nantong, 226631, P. R. China.
Lili FengKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China.
Chenghao YuKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China.
Yanlin ZhuKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China.
Bin LiuKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China.
Zhengxiao GuoDepartment of Chemistry, The University of Hong Kong, Pokfulam, Hong Kong (SAR), 999077, China.
Piaoping YangKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P. R. China.ORCID https://orcid.org/0000-0002-9555-1803

Funding

China Postdoctoral Science Foundation 2023M730825Heilongjiang Provincial Postdoctoral Science Foundation LBH-Z23014National Natural Science Foundation of China 52402340National Natural Science Foundation of China U22A20347National Youth Talent Program, Heilongjiang Natural Science Foundation Project of Outstanding Youth Project YQ2023B005
6 · The paper itself

Abstract

Although metal peroxides are extensively employed in tumor therapy, novel synergistic tumor treatment approaches based on the combination of multiple types of metal peroxides are still lacking and warrant further exploration. To overcome this challenge, hyaluronic acid (HA)-modified bimetallic peroxide nanocomposites (MgO

Indexed as

CopperImmunotherapyNanocompositesNeoplasmsPeroxidesPyroptosisAnimalsCell Line, TumorHumansMiceOxidation-ReductionCopperPeroxidesanti‐tumor immunotherapybimetallic peroxidecuproptosisimmunogenic cell deathpyroptosis

Identifiers

PMID41276916
PMCPMC13042952

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.