Evidence map›Paper›PMID 41276832›Full record

ArticleBMC cancer2025

Impact of laparoscopic surgical proficiency on survival outcomes in laparoscopic radical hysterectomy for cervical cancer: a multi-center cohort study.

Rongjia Su, Dongjian Yang, Sibang Chen, Xiaoyi Ding, Tao Su, Jin Peng, Jiaxi Wang, Xinyu Ni, Roufei Lu, Fengshuang Li and 4 more

Abstract readClinical StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rongjia Su *Department of Gynecology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Municipal Key Clinical Specialty of Gynecologic Oncology, Shanghai, China.
Dongjian Yang *Department of Gynecology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Municipal Key Clinical Specialty of Gynecologic Oncology, Shanghai, China.
Sibang ChenDepartment of Gynecology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Municipal Key Clinical Specialty of Gynecologic Oncology, Shanghai, China.
Xiaoyi DingDepartment of Gynecology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Municipal Key Clinical Specialty of Gynecologic Oncology, Shanghai, China.
Tao SuDepartment of Gynecology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Municipal Key Clinical Specialty of Gynecologic Oncology, Shanghai, China.
Jin PengDepartment of Obstetrics & Gynecology, Qilu Hospital, Shandong University, Jinan Shandong, China.
Jiaxi WangDepartment of Obstetrics & Gynecology, Qilu Hospital, Shandong University, Jinan Shandong, China.
Xinyu NiDepartment of Obstetrics & Gynecology, Qilu Hospital, Shandong University, Jinan Shandong, China.
Roufei LuDepartment of Gynecology, Guangxi Medical University First Affiliated Hospital, Nanning, Guangxi, China.
Fengshuang LiDepartment of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University, Beijing, China.
Jiandong WangDepartment of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University, Beijing, China.
Jiangtao FanDepartment of Gynecology, Guangxi Medical University First Affiliated Hospital, Nanning, Guangxi, China.
Shiqian ZhangDepartment of Obstetrics & Gynecology, Qilu Hospital, Shandong University, Jinan Shandong, China.
Yudong WangDepartment of Gynecology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Municipal Key Clinical Specialty of Gynecologic Oncology, Shanghai, China. wangyudong@shsmu.edu.cn.

Funding

he Central Guidance on Local Science and Technology Development Fund of Shanghai Province YDZX20223100003006
6 · The paper itself

Abstract

objectiveThis study aims to evaluate the impact of gynecologic oncologists' laparoscopic proficiency on survival outcomes in cervical cancer patients.

methodsA cohort of 1,965 cervical cancer cases from four clinical centers in China was analyzed, including abdominal radical hysterectomy (ARH), laparoscopic radical hysterectomy (LRH), and robotic radical hysterectomy (RRH). The median operative time (MOT) for LRH was used as a measure of surgical proficiency. Survival outcomes of ARH vs. LRH were compared in early-stage cervical cancer patients without adjuvant therapy to identify a critical MOT threshold. Below this threshold, no significant differences in prognosis were observed between ARH and LRH. Propensity score matching and mixed-effects Cox regression were used to adjust for baseline risk factors and random effects, validating the finding across all LRH cases.

resultsThe Kaplan-Meier analysis showed that improved prognosis was associated with reduced MOT. When gynecologic oncologists had an MOT within 210 min, LRH vs ARH was no longer a significant risk factor (HR 1.1998; 95% CI: 0.9785-1.4713; p = 0.07998). Propensity score matching and mixed-effects Cox regression were used to further clarify the significant prognostic differences in LRH performed by different level surgeons.

conclusionMOT reflects surgical efficiency and serves as a key indicator of the operative proficiency of gynecologic oncologists, which is pivotal in determining the survival prognosis of cervical cancer patients undergoing LRH. For surgeons with rigorous laparoscopic training, the survival outcomes of LRH are expected to be comparable to those of ARH.

Indexed as

Clinical CompetenceHysterectomyLaparoscopyUterine Cervical NeoplasmsAdultAgedChinaCohort StudiesFemaleHumansKaplan-Meier EstimateMiddle AgedOperative TimePrognosisPropensity ScoreRetrospective StudiesLaparoscopic Radical HysterectomyLaparoscopic Surgical ProficiencyMedian Operative TimeOverall Survival

Identifiers

PMID41276832
PMCPMC12751723

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.